Current EMS treatment guidelines improve survival in patients with TBI who require positive pressure ventilation
Written By : Medha Baranwal
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2024-02-04 12:30 GMT | Update On 2024-02-04 12:30 GMT
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USA: Recently reported results from the Excellence in Prehospital Injury Care (EPIC) study revealed that the implementation of the emergency medical service (EMS) guidelines improves survival in patients with severe traumatic brain injury (TBI). The effect of implementing these guidelines in the subgroup of patients who received positive pressure ventilation (PPV) is unknown.
Joshua B. Gaither, College of Medicine—Phoenix, The University of Arizona, Phoenix, and colleagues conducted a subanalysis of the EPIC study to determine if the implementation of the prehospital TBI evidence-based guidelines impacts survival among patients with prehospital PPV. They found that the guideline implementation was associated with improved survival to hospital admission and discharge among patients with severe TBI who received prehospital PPV. The findings were published online in JAMA Surgery on January 24, 2024.
There is an enormous burden of traumatic brain injury, affecting more than 2.8 million individuals in the US annually. The hope that mitigating secondary brain injury may improve outcomes has led to the promulgation of evidence-based prehospital TBI treatment guidelines. The EPIC study and EPIC4Kids study demonstrated that implementation of the prehospital treatment guidelines was associated with improved survival among patients with severe TBI. This implementation emphasized the prevention and treatment of hypoxia, hyperventilation, and hypotension.
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