Nonoperative management viable option for proximal femoral fractures in frail patients

Netherlands: Nonoperative management of proximal femoral fractures is a viable option for frail institutionalized patients having limited life expectancy, states a recent study in the journal JAMA Surgery. This suggests that for this patient population, surgery should not be a foregone conclusion. 

In frail patients with limited life expectancy, decision-making on management of proximal femoral fractures is challenging but there is a need to prevent surgical overtreatment. Current literature provides limited insight into the true outcomes of nonoperative management and operative management in this patient population.

Pieter Joosse, Department of Surgery, Noordwest Ziekenhuisgroep, the Netherlands, and the colleagues aimed to examine the outcomes of nonoperative management compared to operative management of proximal femoral fractures in institutionalized frail older patients with limited life expectancy in a multicenter cohort study. 

The study was conducted between September 1, 2018, and April 25, 2020 at 25 hospitals across the Netherlands with a 6-month follow-up period. The study included patients aged 70 years or older, frail, and institutionalized and sustained a femoral neck or pertrochanteric fracture. 

The term frail implied the presence of at least 1 of the following characteristics : malnutrition (body mass index [calculated as weight in kilograms divided by height in meters squared] <18.5) or cachexia, severe comorbidities (American Society of Anesthesiologists physical status class of IV or V), or severe mobility issues (Functional Ambulation Category 2).

Exposure was shared decision-making (SDM) followed by nonoperative or operative fracture management. 

The EuroQol 5 Dimension 5 Level (EQ-5D) utility score by proxies and caregivers was the primary outcome. Secondary outcome measures were pain level (assessed by the Pain Assessment Checklist for Seniors With Limited Ability to Communicate), QUALIDEM (a dementia-specific quality-of-life instrument for persons with dementia in residential settings) scores, quality of dying (Quality of Dying and Death Questionnaire), and adverse events (Clavien-Dindo classification), mortality, treatment satisfaction (numeric rating scale). 

"Nonoperative management of proximal femoral fractures following the SDM process is a  viable treatment option for institutionalized frail patients with limited life expectancy," wrote the authors. "A return to preinjury levels of independence ormobility was reached in some patients who were surgically treated, and a postoperative period without AEs was rare."

"Surgery in this specific patient population therefore should not be a foregone conclusion," they concluded.

Reference:

"Evaluation of Quality of Life After Nonoperative or Operative Management of Proximal Femoral Fractures in Frail Institutionalized Patients: The FRAIL-HIP Study," was published in the journal JAMA Surgery.

DOI: 10.1001/jamasurg.2022.0089