Peceleganan spray effective and safe in wound infection, says study.
China: A study entitled "Efficacy and Safety of PL-5 (Peceleganan) Spray for Wound Infections: A Phase IIb Randomized Clinical Trial" has concluded that, for management of wound infection, PL-5 (Peceleganan) spray is the first developed topical antimicrobial peptide (AMP) spray agent. The researchers mentioned both its safety and effectiveness for managing skin wound infections. The optimal concentration given in the study is 2 %.
The study is published in the Annals of Surgery.
Wound infections interfere with the wound-healing process. In addition to intravenous or oral antibiotics, topical antimicrobial agents are frequently used to treat infected skin wounds. Antimicrobial peptide PL-5 spray is a novel topical antimicrobial agent.
The options for topical use remain limited. AMPs are a potential source of pharmaceuticals targeting antibiotic-resistant bacterial infections. There needs to be more data in this context.
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