Perioperative prophylaxis with piperacillin-tazobactam reduces complications following open pancreatoduodenectomy: JAMA
Written By : Aditi
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2023-05-15 04:30 GMT | Update On 2023-05-15 08:43 GMT
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New York: Based on the recent findings from a study published in JAMA Network, piperacillin-tazobactam is effective as perioperative antimicrobial prophylaxis for reducing complications after open pancreatoduodenectomy. Compared to standard care, the percentage of patients with 30-day postoperative surgical site infection was reduced with broad-spectrum piperacillin-tazobactam.
Though perioperative mortality has improved, the incidence of SSI remains high after pancreatoduodenectomy. More data and research is required for the effect of broad-spectrum antimicrobial surgical prophylaxis in reducing SSI.
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