PFAS Exposure Linked to Weight Regain After Teen Bariatric Surgery: Study
A new study published in the journal of Obesity found that higher exposure to endocrine-disrupting PFAS chemicals was associated with increased weight regain in teens post-bariatric surgery, suggesting environmental factors may affect long-term obesity treatment outcomes.
Obesity is still a major public health concern, especially for children, for whom extreme obesity is linked to a higher chance of long-term negative health consequences including heart disease, type 2 diabetes, and a lower quality of life. Over the past several decades, the prevalence of severe obesity in teenagers has increased significantly, highlighting the pressing need for efficient therapies.
In this age range, bariatric surgery has become a successful therapy for extreme obesity, resulting in notable improvements in comorbidities associated with obesity as well as significant initial weight loss. The propensity of many patients to gain weight beyond the first year after bariatric surgery, however, is one of the main obstacles.
Studies have indicated that exposure to the environment may have a significant impact on metabolic health and weight management. Of them, perfluoroalkyl substances (PFAS) have drawn the most attention because of their extensive usage, environmental durability, and endocrine-disrupting properties. Thus, this study was to assess the relationships between PFAS exposure and alterations in adolescents' waist circumference, BMI, and percentage of weight reduction following bariatric surgery.
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