Plasma Presepsin may Diagnose Postoperative Infections with high sensitivity and specificity

When compared to conventional markers such as C-reactive protein (CRP) and procalcitonin (PCT), presepsin emerges as a superior diagnostic tool. It exhibits both heightened sensitivity and specificity across a diverse range of surgical procedures.

These findings observed a significant shift in postoperative care protocols. The potential of presepsin to detect infections promptly offers a ray of hope in mitigating the persistently high rates of postoperative infections. With the promising results, presepsin could become a staple in postoperative monitoring, aiding clinicians in swift and accurate intervention.

While the results are positive, the outcomes of the study emphasize the need for further exploration.  This study could reshape the landscape of postoperative infection detection, offering a potential oppurtunity for countless patients undergoing surgical interventions.

Source:

You, P., Gao, R.-Y., Han, Y.-Z., Zhang, X.-K., Li, W.-X., & Huang, L.-F. (2023). Postoperative plasma presepsin as a biomarker of postoperative infectious complications in different surgical departments: A meta-analysis and systematic review. In The American Journal of Surgery. Elsevier BV. https://doi.org/10.1016/j.amjsurg.2023.11.024