Postoperative chemoprophylaxis in elective abdominal surgery may minimize bleeding risk without compromising VTE protection
A recent study published in the Annals of Surgery recommends initiating chemoprophylaxis postoperatively in elective abdominal surgery cases to reduce bleeding risk while maintaining venous thromboembolisms (VTE) protection.
Venous thromboembolism is a frequent complication in surgical patients. The most prevalent cause of avoidable mortality in individuals hospitalized for surgical operations is pulmonary embolism (PE). The risk of VTE in surgical patients is dictated by a combination of individual predisposing factors and surgical aspects.
Morbidity, mortality, and healthcare expenses are associated with postoperative bleeding and venous thromboembolisms. Chemoprophylaxis is commonly used to prevent VTEs, however it raises the risk of bleeding. The time of chemoprophylaxis initiation during surgery may impact both VTE and hemorrhage risks. The best time to start chemoprophylaxis in the perioperative phase is unknown. As a result, Christopher Klonis and colleagues undertook this study to look at the influence of chemoprophylaxis timing on VTE and bleeding rates in patients awaiting major abdominal surgery.
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