Preoperative thyroid hormone replacement associated with higher risk of complications in major abdominal surgery
USA: A recent study published in The American Journal of Surgery has shed light on the association of preoperative thyroid hormone replacement with perioperative complications following major abdominal surgery.
The study found a 1.5-fold increased risk of severe morbidity and a 1.7-fold greater risk of serious sepsis among individuals on preoperative thyroid replacement before major abdominal surgery. Additionally, patients with pre-existing hypothyroidism on thyroid replacement therapy were more likely to undergo open surgery and also correlated with longer hospital stays rather than minimally invasive procedures.
Patients with pre-existing hypothyroidism are shown to have significantly increased length of stay and increased morbidity. There are opportunities for perioperative optimization and risk stratification based on thyroid replacement.
Considering that the relationship between hypothyroidism and complications following major abdominal surgery has not been elucidated, Matthew E. Spector, University of Pittsburgh, Pittsburgh, PA, USA, and colleagues aimed to determine the association between preoperative thyroid hormone replacement and complications after major abdominal surgery.
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