Robotic surgery improves survival in early-stage oropharyngeal cancer: JAMA
Los Angeles, California: Transoral robotic surgery may improve surgical outcomes and survival in early-stage oropharyngeal cancer patients as compared to nonrobotic surgery, suggests a recent study in the journal JAMA Oncology.
Despite limited comparative data, the use of transoral robotic surgery has been widely adopted since its approval by the US Food and Drug Administration in December 2009. Anthony T. Nguyen, Department of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, California, and colleagues compared the long-term outcomes of transoral robotic surgery with those of nonrobotic surgery for patients with early-stage oropharyngeal cancer.
Retrospective cohort comparative effectiveness analysis was conducted of patients in the National Cancer Database with clinical T1 and T2 oropharyngeal squamous cell carcinoma diagnosed between January 1, 2010, and December 31, 2015, who underwent definitive robotic and non-robotic surgery. To adjust for patient- and disease-related covariates, the researchers performed propensity score matching and multivariable Cox proportional hazards regression analysis. Survival after nonrobotic and robotic surgery was compared in 3 unrelated cancers -- cervical, endometrial, and prostate cancer. The primary outcome was overall survival.
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