Survival in laparoscopic and open liver resection equal in CRC liver metastasis
According to recent research, investigators have found that there was no significant difference between open or laparoscopic liver resection treatment groups, when the survival outcomes were assessed.
This study is published in the Top of FormBottom of FormAnnals of Internal Medicine.
Despite the recent worldwide dissemination of laparoscopic liver surgery, no high-level evidence supports the oncologic safety of this approach. Therefore, Davit L. Aghayan and associates from the Intervention Centre, Oslo University Hospital, Norway conducted the present study on a total of 280 patients to evaluate the long-term oncologic outcomes after laparoscopic versus open liver resection in patients with colorectal metastases.
A single-center, assessor-blinded, randomized controlled trial was performed on patients with resectable colorectal liver metastases who were randomly assigned to have either open or laparoscopic liver resection. Out of the total sample size, 133 patients were assigned to undergo laparoscopic surgery while the remainder were allotted to the open surgery treatment group.
The primary outcome was postoperative morbidity within 30 days. Five-year rates of overall and recurrence-free survival were predefined secondary end points.
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