Anti-inflammatory drugs may prevent death but fail to speed up recovery in COVID-19 patients
An Original Investigation published on July 10, 2023, entitled, "Abatacept, Cenicriviroc, or Infliximab for Treatment of Adults Hospitalized With COVID-19 Pneumonia A Randomized Clinical Trial" by Dr Jane and colleagues published in JAMA concluded that among hospitalized patients with COVID-19 pneumonia, time to recovery is not decreased by Abatacept, cenicriviroc, or infliximab in comparison with standard care.
It is already known that there is an association between Immune dysregulation and poorer outcomes in COVID-19. Considering this, the present team of researchers investigated whether abatacept, cenicriviroc, or infliximab provides benefits when added to standard care for COVID-19 pneumonia. (3 substudies reported from 95 hospitals at 85 clinical research sites in the US and Latin America). They measured time to recovery by day 28 evaluated using an 8-point ordinal scale as the primary outcome
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