Two key proteins that control heart growth identified
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London – Researchers have identified how two proteins control the growth of the heart and its adaptation to high blood pressure that can help design new strategies to treat heart failure caused by excessive growth of the heart.
The research, carried out by lead investigator Guadalupe Sabio from the National Centre for Cardiovascular Research (CNIC) in Spain, shows for the first time that two proteins – p38 gamma and p38 delta – control heart growth.
“This new information could help in the design of new strategies to combat heart conditions caused by anomalous growth of heart muscle,” said Sabio in a paper in the journal Nature Communications.
The heart adapts to the changing needs of each stage of life by adjusting its size.
In this way the heart grows in line with the rest of our body, including during pregnancy, in a process called cardiac hypertrohpy.
The research, carried out by lead investigator Guadalupe Sabio from the National Centre for Cardiovascular Research (CNIC) in Spain, shows for the first time that two proteins – p38 gamma and p38 delta – control heart growth.
“This new information could help in the design of new strategies to combat heart conditions caused by anomalous growth of heart muscle,” said Sabio in a paper in the journal Nature Communications.
The heart adapts to the changing needs of each stage of life by adjusting its size.
In this way the heart grows in line with the rest of our body, including during pregnancy, in a process called cardiac hypertrohpy.
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