Acute urinary retention a clinical marker of prostate and other cancers: BMJ

Written By :  Meghna A Singhania
Medically Reviewed By :  Dr. Kamal Kant Kohli
Published On 2021-10-28 03:30 GMT   |   Update On 2021-10-29 11:53 GMT
Advertisement

Acute urinary retention is a clinical marker of prostate and other cancers, according to a study published in the BMJ.

A group of researchers from Denmark conducted a nationwide population-based cohort study in all hospitals in Denmark to examine the risk of urogenital, colorectal, and neurological cancers after the first diagnosis of acute urinary retention.

The researchers included a total of 75 983 patients aged 50 years or older with first hospital admission for acute urinary retention during 1995-2017.

The primary measures and outcomes were Absolute risk of urogenital, colorectal, and neurological cancer and excess risk of these cancers among patients with acute urinary retention compared with the general population.

The results of the study are as follows:

  • The absolute risk of prostate cancer after the first diagnosis of acute urinary retention was 5.1% (n=3198) at three months, 6.7% (n=4233) at one year, and 8.5% (n=5217) at five years.
  • Within three months of follow-up, 218 excess cases of prostate cancer per 1000 person-years were detected.
  • An additional 21 excess cases per 1000 person-years were detected during three to less than 12 months of follow-up, but beyond 12 months the excess risk was negligible.
  • Within three months of follow-up, the excess risk for urinary tract cancer was 56 per 1000 person-years, for genital cancer in women was 24 per 1000 person-years, for colorectal cancer was 12 per 1000 person-years, and for neurological cancer was 2 per 1000 person-years.
  • For most of the studied cancers, the excess risk was confined to within three months of follow-up, but the risk of prostate and urinary tract cancer remained increased during three to less than 12 months of follow-up.
  • In women, an excess risk of invasive bladder cancer persisted for several years.

Thus the researchers concluded that acute urinary retention might be a clinical marker for occult urogenital, colorectal, and neurological cancers. Occult cancer should possibly be considered in patients aged 50 years or older presenting with acute urinary retention and no obvious underlying cause.

Reference:

Acute urinary retention and risk of cancer: population-based Danish cohort study by Maria Bisgaard Bengtsen et al published in the BMJ

doi: https://doi.org/10.1136/bmj.n2305


Tags:    
Article Source : BMJ

Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.

NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.

Our comments section is governed by our Comments Policy . By posting comments at Medical Dialogues you automatically agree with our Comments Policy , Terms And Conditions and Privacy Policy .

Similar News