CT based scoring system accurately predicts outcome for clinical LN in bladder cancer patients: Study

The results of the study are as follows:

· 764 cN0 and 166 cN+ patients with complete follow-up and imaging data were included in the study.

· Accuracy to detect LN metastasis and locally advanced tumour stage in CT scan was 72% and 62%. LN larger than 15mm in diameter were significantly associated with higher LNR.

· Increased NLN correlated with decreased CSS and OS.

· Furthermore, CT scan-based scoring system precisely differentiates low-risk and high-risk profiles to predict the oncological outcomes.

Thus, the researchers concluded that solely LN size >15mm significantly correlated with higher lymph node ratio (LNR). Identification of increased loco-regional lymph node was associated with worse survival. For the first time, precise risk stratification based on computed-tomography findings was developed to predict the oncological outcomes for clinical lymph node-positive patients undergoing radical cystectomy (RC).

Reference:

Computed-tomography based scoring system predicts outcome for clinical lymph node-positive patients undergoing radical cystectomy by Eismann L et. al published in the International Brazilian Journal of Urology.

DOI: 10.1590/S1677-5538.IBJU.2021.0329