Sarcopenia, new prognostic marker in penile cancer patients: Study
Japan: A low volume psoas muscle is associated with poor prognosis in penile cancer, according to a recent study in the journal Oncotarget.
Sarcopenia is a condition characterized by low muscle volume due to aging. Recently, it has been studied as a risk factor predicting an increased risk of postoperative complications and longer hospitalization. Previous studies have shown the importance of sarcopenia as a risk factor for poor survival in renal and bladder cancer.
Penile cancer is accounting for only 0.5% of all cancer in men. Lymph node metastatic cases show a poor prognosis while localized penile cancer tends to have a relatively favorable outcome. However, with complete resection of the metastatic lymph node, even cases of lymph node metastasis can show a favorable outcome.
A previous study has shown a higher incidence of postoperative complications in sarcopenic penile cancer patients who underwent inguinal lymph node dissection than patients without sarcopenia. Daiji Takkamoto, Yokohama City University Medical Center, Yokohama, Japan, and colleagues therefore examined the importance of sarcopenia as a new prognostic marker in penile cancer.
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