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High Apolipoprotein B- Potential Risk Factor for CVD: Latest Indian Experience - Video

Published On 2024-07-30T12:27:00+05:30  |  Updated On 6 Aug 2024 11:28 AM IST
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Overview

Elevated levels of apolipoprotein B is a potential risk factor for cardiovascular disease (CVD) among Indians, a recent study has reported. The association between high Apo B levels & LDL-C indicates a potential risk factor for CVD.

The research has been published in the July 2024 issue of International Journal of Scientific Research. This cross-sectional observational study included 69 participants.

Here are some of the key observations from this study:

  • Participants aged 36-50 years exhibited significantly higher mean levels of apolipoprotein B compared to those aged ≤35 years and those over 50 years.

Each 10 mg/dl reduction in Apo B leads to a reduction in coronary heart disease by 9% & major CVD risk by 6%1. Rosuvastatin 40 mg offers a significant reduction in Apo B by 37%2.

The study highlights the burden of high Apo B levels as a CV risk factor, emphasizing the need for monitoring and managing Apo B levels to alleviate CVD risk in clinical practice.

References:

1) Robinson JG, Wang S, Jacobson TA. Meta-analysis of comparison of effectiveness of lowering apolipoprotein B versus low-density lipoprotein cholesterol and nonhigh-density lipoprotein cholesterol for cardiovascular risk reduction in randomized trials. Am J Cardiol. 2012 Nov 15;110(10):1468-76. doi: 10.1016/j.amjcard.2012.07.007. Epub 2012 Aug 17. PMID: 22906895.

2) Pitt B, Loscalzo J, Monyak J, Miller E, Raichlen J. Comparison of lipid-modifying efficacy of rosuvastatin versus atorvastatin in patients with acute coronary syndrome (from the LUNAR study). Am J Cardiol. 2012 May 1;109(9):1239-46. doi: 10.1016/j.amjcard.2011.12.015. Epub 2012 Feb 21. PMID: 22360820.

3) Understanding The Correlation Between Apolipoprotein B And Ldl Cholesterol, Sheetal Kamat, Mohd Shahid, Lalit Kumar Garg, Santosh Revankar, International Journal Of Scientific Research 2024;13(7):1-3

Speakers

Dr. Nandita Mohan

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751
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