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  • ESRD patients...

ESRD patients undergoing PCI have considerably higher length of hospital stay and mortality

Written By : Dr.Niharika Harsha B |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2023-05-31T20:00:00+05:30  |  Updated On 31 May 2023 8:00 PM IST
ESRD patients undergoing PCI have considerably higher length of hospital stay and mortality
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New research has revealed that End stage renal disease patients undergoing percutaneous coronary intervention have considerably higher In-hospital outcomes like mortality, cost, and length of stay than those not having the end-stage renal disease. The study results were published in the journal Cardiovascular Revascularization Medicine.

When the kidneys can no longer carry out their normal function, a person has end-stage renal disease and needs renal replacement treatment or a kidney transplant. The major cause of mortality for those with end-stage renal disease (ESRD) is cardiovascular disease due to increased coronary plaque and calcifications leading to a hyper-inflammatory state. Previous literature has shown that ESRD patients undergoing percutaneous coronary intervention (PCI) have an increase in in-hospital mortality and prolonged hospitalization, among other complications when compared with non-ESRD patients undergoing the same procedure. Hence researchers conducted a study to evaluate the in-hospital mortality after PCI in the setting of Acute Coronary Syndrome (ACS) using the National Inpatient Database (NIS) between the years 2016–2019 in ESRD patients.

Also Read: Genetic risks for Spontaneous Coronary Artery Dissection largely affecting younger women revealed in study

Patients who had PCI between 2016 and 2019 were identified using the national inpatient sample (NIS). Patients with ESRD receiving renal replacement therapy (RRT) were then put into separate groups. In-hospital mortality was evaluated using logistic regression models as the primary outcome, while hospitalization costs and duration of stay were evaluated using linear regression models as the secondary outcomes.

Key findings:

  • Nearly 21,366 unweighted observations were initially included, which had 50 % ESRD patients and 50 % randomly selected patients without ESRD who underwent PCI.
  • A nationwide estimate of 106,830 patients was represented by these weighted observations.
  • The mean age of the study population was 65 years, and 63 % of the patients were male.
  • The ESRD group had a greater representation of minority groups compared to the control group.
  • ESRD group showed a significantly higher in-hospital mortality rate when compared to the control group, with an odds ratio of 1.803.
  • The ESRD group also had a significantly higher healthcare cost and longer length of stay, with a mean difference of $47,618 and 2.933 days.

Thus, the In-hospital mortality, cost, and length of hospital stay for patients undergoing PCI in the setting of ACS were found to be significantly greater in the ESRD group.

Further reading: In-hospital outcomes of PCI in patients who have ESRD vs non-ESRD patients, a retrospective study involving a National Inpatient Sample (NIS) database. https://doi.org/10.1016/j.carrev.2023.05.016


cardiovascular Revascularization MedicineCardiovascular diseasesHeartCardiologyNephrologyCardiovascular health
Source : Cardiovascular Revascularization Medicine
Dr.Niharika Harsha B
Dr.Niharika Harsha B

    BDS, MDS

    Dr.Niharika Harsha B (BDS,MDS) completed her BDS from Govt Dental College, Hyderabad and MDS from Dr.NTR University of health sciences(Now Kaloji Rao University). She has 4 years of private dental practice and worked for 2 years as Consultant Oral Radiologist at a Dental Imaging Centre in Hyderabad. She worked as Research Assistant and scientific writer in the development of Oral Anti cancer screening device with her seniors. She has a deep intriguing wish in writing highly engaging, captivating and informative medical content for a wider audience. She can be contacted at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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