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Incidence of Spontaneous coronary artery dissection on the rise, finds study
Incidence of Spontaneous coronary artery dissection is on the rise finds study published in the International Journal of Cardiology.
Spontaneous coronary artery dissection (SCAD) has been described as an infrequent cause of acute coronary syndrome (ACS). Knowledge about the disease is still limited and SCAD might still be underdiagnosed.
Patients with SCAD between 1997 and 2021 at the University Hospital Zurich, Switzerland, were included. Incidences were assessed as total numbers and proportions of ACS cases. Clinical data were collected from medical records and angiographic findings were reviewed. Major adverse cardiac events (MACE) were defined as the composite of all-cause death, cardiac arrest, SCAD recurrence or progression, other myocardial infarction, and stroke.
Results
One hundred fifty-six SCAD cases were included in this study. The incidence increased significantly in total (p < 0.001) and relative to ACS cases (p < 0.001). This was based on an increase of shorter lesions (p = 0.004), SCAD type 2 (p < 0.001), and lesions in side branches (p = 0.014), whereas lesions in the left main coronary artery and proximal segments were decreasing (p-values 0.029 and < 0.001, respectively). There was an increase in conservative therapy (p < 0.001). The rate of MACE (24%) was stable, however, there was a reduced proportion of patients with a need for intensive care treatment (p = 0.017).
SCAD represents an important entity of ACS that still might be underappreciated. The increasing incidence of SCAD is likely based on better awareness and familiarity with the disease. A lower need for intensive care treatment suggests positive effects of the increasing implementation of conservative management.
Reference:
Michael Würdinger, Victor Schweiger, Thomas Gilhofer, Victoria L. Cammann, Annika Badorff, Iva Koleva, Davide Di Vece, David Niederseer, Alessandro Candreva, Jonathan Michel, Alexander Gotschy, Julia Stehli, Barbara E. Stähli, Jelena R. Ghadri, Christian Templin. Twenty-five-year trends in incidence, angiographic appearance, and management of spontaneous coronary artery dissection, International Journal of Cardiology,Volume 395,
2024,131429,ISSN 0167-5273,https://doi.org/10.1016/j.ijcard.2023.131429.
(https://www.sciencedirect.com/science/article/pii/S0167527323014596)
Keywords:
Incidence, Spontaneous, coronary artery, dissection, rise, International Journal of Cardiology, Spontaneous coronary artery dissection; SCAD; Trends; Incidence; Types; Management, Michael Würdinger, Victor Schweiger, Thomas Gilhofer, Victoria L. Cammann, Annika Badorff, Iva Koleva, Davide Di Vece, David Niederseer, Alessandro Candreva, Jonathan Michel, Alexander Gotschy, Julia Stehli, Barbara E. Stähli, Jelena R. Ghadri, Christian Templin
Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751