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Novel post-closure technique reduces vascular complications related to Impella CP removal
USA: A novel post-closure technique for removal of next-generation Impella CP and immediate hemostasis may reduce vascular complications tied to devise removal and may improve clinical outcomes in these patients, the researchers claim in a new study. "The post-closure technique uses the side port of the next generation Impella CP to introduce a 0.035″ guidewire to maintain femoral...
USA: A novel post-closure technique for removal of next-generation Impella CP and immediate hemostasis may reduce vascular complications tied to devise removal and may improve clinical outcomes in these patients, the researchers claim in a new study.
"The post-closure technique uses the side port of the next generation Impella CP to introduce a 0.035″ guidewire to maintain femoral vascular access," the researchers explain in their study published in the journal Cardiovascular Revascularization Medicine.
"The Impella CP is removed, a 14F sheath is placed and a second 0.035″ wire is introduced through the 14F sheath in an over-the-wire, rapid exchange fashion," they wrote. "This allows for a double-wire approach to deploy two suture-mediated closure devices at the time of the extraction of the device of immediate hemostasis in the cath lab."
In an over-the-wire, rapid exchange fashion, the Impella CP is removed, a 14F sheath is placed and a second 0.035″ wire introduced through the 14F sheath, which allows for a double-wire approach to deploy two suture-mediated closure devices at the time of device extraction for immediate hemostasis in the cardiac catheterization lab
There has been an exponential growth in the use of percutaneous mechanical circulatory support. Vascular complications remain a growing concern and there are no best practices for device removal. In the study, Colin S.Hirst, Ascension Saint John Heart and Vascular Institute, Ascension Saint John Hospital, Detroit, MI, USA, and colleagues describe a novel post-closure technique for the next generation Impella CP removal and immediate hemostasis. They aimed to determine if the post-closure technique reduces access site adverse vascular events (AVE) and bleeding when compared to manual compression upon device removal of the next generation Impella CP.
For this purpose, the researchers conducted a single-center, retrospective, exploratory analysis of 11 consecutive patients receiving an Impella CP for either high-risk PCI or cardiogenic shock and then referred for post-closure. They were compared to 20 patients receiving manual compression for Impella CP removal between 2017 and 2019. The mean age range was 62.7–65.4 years and 50–65% were male.
Salient findings of the study include:
- The average duration of Impella CP treatment ranged from 3.4 to 5.2 days.
- Patients referred for post-closure had significantly lower rates of all-cause adverse vascular events (0% versus 40%; n = 0/11 versus n = 8/20).
- There was no significant difference in BARC 3 or greater bleeding, transfusion requirement, hospitalization duration or intensive care duration between removal strategies.
"The novel post-closure technique significantly decreases vascular complications associated with device removal and may improve clinical outcomes for these critically ill patients," the authors concluded.
Hirst CS, Thayer KL, Harwani N, Kapur NK. Post-closure technique to reduce vascular complications related to Impella CP. Cardiovasc Revasc Med. 2021 Nov 3:S1553-8389(21)00686-2. doi: 10.1016/j.carrev.2021.10.008. Epub ahead of print. PMID: 34810113.
Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at firstname.lastname@example.org. Contact no. 011-43720751