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  • Prenatal depression...

Prenatal depression increases postpartum cardiovascular disease risk: JAHA Study

Written By : Dr. Mahalakshmi Sivashankaran |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2023-08-02T09:30:48+05:30  |  Updated On 2 Aug 2023 3:07 PM IST
Prenatal depression increases postpartum cardiovascular disease risk: JAHA Study
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USA: According to a new study published in JAHA: Journal of American Heart Association, pregnant individuals with prenatal depression have an increased risk of developing cardiovascular disease (CVD) in the first two years postpartum.

The study aimed to assess the cumulative risk of new CVD in the first 24 months after birth between pregnant women who had prenatal depression and those who did not have depression throughout pregnancy.

The study conducted by researchers at the Maine Medical Center included over 119,422 pregnancies from 2007-2019 with Maine Health Data Org.'s claims data, excluding those with certain conditions. Depression and CVD were identified by ICD-9/10 codes, and hazard ratios were estimated with Cox models. Analyses were stratified by a hypertensive disorder of pregnancy.

The study revealed the following key takeaways:

1. Prenatal depression was associated with an increased risk of ischemic heart disease, arrhythmia/cardiac arrest, cardiomyopathy, and new hypertension.

2. Adjusted hazard ratios ranged from 1.32 to 1.83, which indicates a statistically significant increased risk of CVD in pregnant individuals with prenatal depression compared to those without depression.

3. Several of these associations persisted even when stratified by co-occurring hypertensive disorders of pregnancy.

These findings are particularly important given that depression is a common complication during pregnancy, affecting up to 20% of women. If left untreated, prenatal depression can have negative impacts on both the mother and the baby. This study suggests that there may be short-term as well as long-term implications.

The researchers of the study said that “Further research is needed to determine the causal pathway between prenatal depression and postpartum CVD. However, they suggest that these findings can inform postpartum CVD preventive measures. This may include increased screening and monitoring for depression during pregnancy, as well as providing appropriate mental health treatment when needed.”

Reference:

Ackerman-Banks C., Lipkind H., Palmsten K., Pfeiffer M., Gelsinger C., Ahrens K.; Association of Prenatal Depression With New Cardiovascular Disease Within 24 Months Postpartum; Journal of the American Heart Association. 2023;0:e028133; doi: https://doi.org/10.1161/JAHA.122.028133

Prenatal depressiondepressiondepression during pregnancypostpartum cardiovascular diseasecardiovascular disordercardiac arrestscardiomyopathyhypertensive disorderJournal of the American Heart Association(JAHA)JAHA
Article Source :  JAHA: Journal of American Heart Association
Dr. Mahalakshmi Sivashankaran
Dr. Mahalakshmi Sivashankaran

    Dr. Mahalakshmi Sivashankaran joined Medical Dialogues as an Intern in 2023. She is a BDS graduate from Manipal College of Dental Sciences, Mangalore Batch 2022, and worked as a Junior Resident at VMMC & Safdarjung Hospital at the Department of Dental Surgery till January 2023. She has completed a Diploma in Executive Healthcare management from the Loyola Institute of Business Administration, developing skills in Healthcare Management and Administration. She covers several medical specialties including Dental, ENT, Diagnostics, Pharmacology, Neurology, and Cardiology.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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