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Untreated hypertension patients at high risk of open-angle glaucoma
Korea: According to a study published in the American Journal of Ophthalmology, researchers have concluded that the risk of open-angle glaucoma increases with the risk of untreated blood pressure.
Hypertension (HTN) is associated with open-angle glaucoma (OAG). The question is whether elevated blood pressure (BP) alone is associated with OAG.
There needs to be more research and data on Whether stage 1 hypertension increases the disease risk, as per the 2017 American College of Cardiology/American Heart Association (ACC/AHA) BP guidelines.
The researchers in the present retrospective, observational cohort study investigated the above background, including 360,330 subjects ≥40 years and not taking antihypertensive drugs or antiglaucoma drugs at the time of examinations.
The categories of Subjects were untreated BP, into normal BP (systolic BP (SBP)<120 and diastolic BP (DBP)<80 mmHg; n=104,304), elevated BP (SBP 120-129 and DBP<80mmHg; n=33,139), stage 1 HTN (SBP 130-139 or DBP 80-89 mmHg; n=122,534) or stage 2 HTN (SBP≥140 or DBP≥90mmHg; n=100,353).
The study summary is :
- Among the participants, 56.2 % were male, with a mean age of 51.17±8.97 years.
- The mean follow-up period was 11.76±1.37 years.
- Twelve thousand eight hundred forty-one subjects had OAG.
- Multivariable-adjusted HRs for elevated BP, stage 1 HTN and stage 2 HTN with normal BP as the reference were 1.056, 1.101 and 1.114, respectively.
Concluding further, they said OAG risk increases with increases in untreated BP.
They mentioned Stage 1 HTN as a significant risk factor for OAG. The study has addressed the role of screening and monitoring for glaucoma in those diagnosed with hypertension.
Further reading:
Increased risks of open-angle glaucoma in untreated hypertension. https://doi.org/10.1016/j.ajo.2023.03.032
BDS, MDS in Periodontics and Implantology
Dr. Aditi Yadav is a BDS, MDS in Periodontics and Implantology. She has a clinical experience of 5 years as a laser dental surgeon. She also has a Diploma in clinical research and pharmacovigilance and is a Certified data scientist. She is currently working as a content developer in e-health services. Dr. Yadav has a keen interest in Medical Journalism and is actively involved in Medical Research writing.
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751