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BPLTTC: Using Antihypertensive agents as risk modifiers for prevention of CV events irrespective of baseline criteria: Scope of Amlodipine
Hypertension, a prominent cause of premature mortality, affects ~1.13 billion people worldwide, though blood pressure (BP) control rates remain dismal at <20%. (1) Though several trials have shown that BP-lowering with antihypertensive agents is an effective strategy for reducing cardiovascular (CV) risk, the treatment and control rates of patients with hypertension (BP>140/90 mm Hg) across the world remain disappointing.
This discrepancy can be partly attributed to the fact that ambiguities continue to exist about the efficacy and safety of BP-lowering. Some of the issues include the lack of expert consensus on the suitable BP threshold for initiation of therapy and whether this should vary based on the patient's age or baseline disease status. Similarly, data is frugal on the effects of antihypertensive therapy on safety and non- vascular outcomes. (2)
Dr Prem Aggarwal, (MD Medicine, DNB Cardiology) is a Cardiologist by profession and also the Co-founder of Medical Dialogues. He is the Chairman of Sanjeevan Hospital in Central Delhi and also serving as the member of Delhi Medical Council
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: editorial@medicaldialogues.in. Contact no. 011-43720751