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Rare Disease Show Episode 22: Understanding Amyloidosis with Dr Sanju Daniel John - Video

Published On 2024-12-31T08:45:22+05:30  |  Updated On 31 Dec 2024 8:45 AM IST
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Overview

Medical Dialogues presents a rare disease series, delving into the realm of uncommon medical conditions. Rare diseases are medical conditions that affect only a small percentage of the population.

Throughout this series, we'll discuss these rare diseases in various episodes, with medical experts providing clear explanations and insights.

Rare Disease Show Episode 21: In today's show we will cover Amyloidosis.

Amyloidosis is a rare disease caused by the build-up of abnormal proteins called amyloids in organs and tissues. These amyloid deposits can affect various organs, including the heart, kidneys, liver, and nervous system, disrupting their normal function.

Symptoms vary depending on the affected organ, but may include fatigue, swelling, and organ dysfunction. Treatment focuses on managing symptoms, halting amyloid production, and preventing further damage, with options including chemotherapy, stem cell transplants, and medications to reduce amyloid production.Early diagnosis is crucial for better outcomes.

In this episode, Dr Sanju Daniel John, Consultant in Internal Medicine at Apollo Adlux Hospital, Angamaly, Ernakulam shares his insights by addressing questions asked by the Medical Dialogues team-

1. Can you explain what amyloidosis is, why is it classified as a rare disease?

2. What are the most common forms of amyloidosis that you encounter in clinical practice?

3. What are the key diagnostic steps you take when you suspect a patient might have amyloidosis?

4. How important is a tissue biopsy in confirming an amyloidosis diagnosis? Are there non-invasive diagnostic tools that can also be effective?

5. Could you describe the pathophysiology behind amyloidosis? How do amyloid deposits disrupt normal tissue function?

6. How does amyloid fibril deposition affect organs differently (e.g., kidneys, heart, nervous system)?

7. What are the treatment options available for patients with amyloidosis, and how do you decide on the best course of treatment?

8. What is the role of chemotherapy and stem cell transplant in treating systemic amyloidosis?

9. How do you manage patients with cardiac amyloidosis? Are there any recent advancements in treatment for this specific form?

10. How do you approach the management of organ involvement, such as renal or liver amyloidosis, to prevent further damage?

11. What are some of the most challenging aspects of managing patients with amyloidosis from a clinical perspective?

Speakers

Dr. Nandita Mohan

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

Dr Sanju Daniel John

Dr Sanju Daniel John (MBBS, MD (General Medicine)) is a Consultant in Internal Medicine at Apollo Adlux Hospital, Angamaly, Ernakulam, with 12 years of experience. He specializes in managing diabetes across all age groups and has expertise in treating lifestyle diseases, infectious diseases, geriatric conditions, and providing critical care. Dr John earned his MBBS and MD in General Medicine from Father Muller Medical College, Mangalore, Karnataka. He has further enhanced his qualifications with a Fellowship in Diabetology from Medigrad, New Delhi, and a Fellowship in Infectious Diseases from Medvarsity. Additionally, he has undergone specialized training in Geriatric Medicine at Apollo Hospital, Medvarsity, and completed a Basic Course in Biomedical Research from the ICMR-National Institute of Epidemiology. Dr John has contributed to numerous projects and publications. Notably, he participated as an investigator in an international study published in the International Journal of Recent Trends in Science and Technology. The study examined the management of thrombocytopenia associated with Plasmodium vivax malaria at a tertiary care center in Southern India.
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