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  • High dose Vitamin D...

High dose Vitamin D supplementation may reduce ICU admission rates in Covid-19 patients

Written By : Niveditha Subramani |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2023-11-19T19:00:01+05:30  |  Updated On 19 Nov 2023 7:00 PM IST
High dose Vitamin D supplementation may reduce ICU admission rates in Covid-19 patients
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The recent global pandemic has gained a lot of interest, several clinical trials and studies are being conducted even after the pandemic to face the detrimental effects of the COVID-19 virus, researchers and physicians try to discover possible treatments to improve the outcome of their patients

A new study reports vitamin D supplementation was associated with reduced ICU admission and mechanical ventilation rates in patients with SARS-CoV-2 infection. However, vitamin D supplementation did not significantly affect mortality associated with SARS-CoV-2 infection. The study is published in Nutrients.

Vitamin D’s potential role in COVID-19 prevention and treatment has gained the limelight. Some studies have suggested that individuals with low levels of vitamin D may be at increased risk of severe illness from COVID-19.

A systematic review and meta-analysis were conducted to evaluate the efficacy of vitamin D supplementation in COVID-19, focusing on length of hospital stay (LOS), admission to the intensive care unit (ICU), and mortality.

The key findings of the study are

• Thirteen randomized controlled trials (RCTs) were included, and the meta-analysis revealed that high-dose vitamin D supplementation showed potential benefits in reducing the length of hospital stay and ICU admission rates for patients with COVID-19.

• However, the overall effect on mortality did not reach statistical significance. While this systematic review suggests the potential benefits of high-dose vitamin D supplementation in reducing hospital stays and ICU admission in COVID-19 patients, caution is warranted due to the high heterogeneity and limitations of the included studies.

Further large-scale randomized controlled trials with consistent study characteristics are needed to provide more robust evidence regarding the therapeutic benefits of vitamin D supplementation in COVID-19 outcomes they ended.

Reference: Sîrbu AC, Sabin O, Bocșan IC, Vesa ȘC, Buzoianu AD. The Effect of Vitamin D Supplementation on the Length of Hospitalisation, Intensive Care Unit Admission, and Mortality in COVID-19-A Systematic Review and Meta-Analysis. Nutrients. 2023 Aug 5;15(15):3470. doi: 10.3390/nu15153470.

Vitamin D supplementsICU admissionCovid-19 patientsglobal pandemiclength of hospital stayNutrients
Source : Nutrients.
Niveditha Subramani
Niveditha Subramani

    MSc. Neuroscience

    Niveditha Subramani a MSc. Neuroscience (Faculty of Medicine) graduate from University of Madras, Chennai. Ambitious in Neuro research having worked in motor diseases and neuron apoptosis is interested in more of new upcoming research and their advancement in field of medicine. She has an engrossed skill towards writing and her roles at Medical dialogue include Sr. Content writer. Her news covers new discoveries and updates in field of medicine. She can be reached at editorial@medicaldialogues.in

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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