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  • Add on Collagen...

Add on Collagen Membranes over titanium meshes not necessary in GBR-Based VRA: Study

Dr. Shravani DaliWritten by Dr. Shravani Dali Published On 2025-08-07T21:00:59+05:30  |  Updated On 7 Aug 2025 9:01 PM IST
Add on Collagen Membranes over titanium meshes not necessary in GBR-Based VRA: Study
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A new study published in the Journal of Functional Biomaterials suggests that the routine addition of collagen membranes over titanium meshes or titanium-reinforced membranes may not be essential in guided bone regeneration (GBR) procedures for vertical ridge augmentation (VRA). The researchers conducted a systematic review and meta-analysis of available animal studies and found no significant benefit in bone gain or complication rates when a collagen membrane was layered on top of titanium meshes. This challenges a widely practiced clinical step and raises questions about its necessity, especially considering cost, surgical complexity, and material handling. While titanium meshes already provide structural stability and space maintenance during bone regeneration, the added membrane may not further enhance clinical outcomes in all cases. The authors emphasize, however, that these findings are based on preclinical data, and well-designed human randomized controlled trials are needed to confirm the results before any changes to current protocols are recommended. Still, the study opens a conversation around simplifying GBR protocols and reducing biomaterial use where it may not offer added value. Until human evidence emerges, clinicians are advised to weigh the risks and benefits on a case-by-case basis.

Reference:
Almeida, B., Duda, F., Granato, R., & Araujo, M. (2024). Do collagen membranes placed over titanium meshes or titanium-reinforced membranes influence outcomes of guided bone regeneration for vertical ridge augmentation? A systematic review. Journal of Functional Biomaterials, 16(7), 246. https://doi.org/10.3390/jfb16070246

Keywords: guided bone regeneration, vertical ridge augmentation, titanium mesh, collagen membrane, bone grafting, GBR protocol, dental implants, membrane layering, Journal of Functional Biomaterials, Almeida et al.



guided bone regenerationvertical ridge augmentationtitanium meshcollagen membranebone graftingGBR protocoldental implantsmembrane layeringJournal of Functional Biomaterials
Source : Journal of Functional Biomaterials
Dr. Shravani Dali
Dr. Shravani Dali

    Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

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