APAP-MAD therapy combo significantly decreased daytime sleepiness among sleep apnea patients

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2022-12-18T20:00:45+05:30 | Updated On 19 Dec 2022 12:48 PM IST

APAP-MAD therapy combo significantly increased compliance with APAP therapy among patients with moderate-to-severe OSA suggests a recent study published in the European Journal of Dentistry.

The purpose of this pilot study was to determine whether compliance to auto-adjusting positive airway pressure (APAP) improves with the addition of a mandibular advancement device (MAD). Secondary outcome measures included were APAP pressure, subjective daytime sleepiness, apnea–hypopnea index (AHI), and mask leaks.

Participants included were diagnosed with moderate-to-severe obstructive sleep apnea (OSA) and became noncompliant to prescribed APAP. Thirteen participants with a mean age of 61.6 years were recruited for this study. All participants were given a MAD to use with their APAP. Parameters measured included APAP pressure, AHI, mask leak reported via ResMed AirViewTM software, and self-reported daytime sleepiness (Epworth Sleepiness Scale [ESS]). A paired two-sample for mean t-test was performed to determine significance.

Results:

• The mean difference of pre- and postintervention APAP compliance was 23.1%, which was statistically significant (p = 0.015).

• The mean APAP air pressures were unchanged.

• The difference between pre- and postintervention mean ESS scores was 1.4 and was statistically significant (p = 0.027).

• The mean difference between pre- and postintervention AHI values and mask leak showed no significant difference.

This study showed that combination of APAP-MAD therapy, for patients with moderate-to-severe OSA who were noncompliant to APAP use, significantly increased compliance with APAP therapy, and significantly decreased the daytime sleepiness of participants.

Reference:

Thyagaseely Sheela Premaraj , Jacob Stadiem , Shyamaly Arya Premaraj , Charles R. Davies , Matthew Dennis , John J. Harrington. Continuous Positive Airway Pressure-Mandibular Advancement Device Combination Therapy for Moderate-to-Severe Obstructive Sleep Apnea: A Preliminary Study. CC BY 4.0 · Eur J Dent 2022; 16(04): 749-755. DOI: 10.1055/s-0040-1719220

Keywords:

APAP-MAD, therapy, combo ,significantly, increased, compliance, APAP, therapy, patients moderate-to-severe OSA, Thyagaseely Sheela Premaraj , Jacob Stadiem , Shyamaly Arya Premaraj , Charles R. Davies , Matthew Dennis , John J. Harrington

European Journal of Dentistryauto-adjusting positive airway pressureEpworth Sleepiness Scale scoresmandibular advancement deviceobstructive sleep apnea

Source : European Journal of Dentistry

Dr. Shravani Dali

Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751