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  • EGCG may improve...

EGCG may improve outcome of periodontal non-surgical periodontal treatment: Study

Written By : Dr. Nandita Mohan |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2021-02-23T09:45:52+05:30  |  Updated On 23 Feb 2021 2:01 PM IST
EGCG may improve outcome of periodontal non-surgical   periodontal treatment: Study
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Researchers have observed that the purified Epigallocatechin Gallate showed the potential to improve the outcome of periodontal non-surgical treatment and the new-type scaler tip provided an alternative vehicle for subgingival medication.

The study is published in the BMC Oral Health Journal.

Epigallocatechin Gallate (EGCG) as green tea catechins possessed antibacterial and anti-inflammatory effects on periodontal disease. Green tea catechins extracted from Camellia sinesis have been reported to possess an antibacterial effect against gram-negative anaerobic rods. Mechanical debridement as scaling and root planing (SRP) has been repeatedly demonstrated to be effective to remove subgingival pathogens and lead to an improvement of periodontal status.

Therefore, Yanfeng Wang and colleagues from the Department of Periodontology, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing, China conducted this study to evaluate the clinical and microbiological efficacy of scaling and root planing (SRP) using EGCG aqueous solution as coolants through a new-type ultrasonic scaler tip on chronic periodontitis.

This split-mouth, the randomized clinical trial included 20 patients (2 drop-outs) with chronic periodontitis and the maxillary contra-lateral sides were allocated into test and control groups randomly. Through the new-type scaler tip, 762 sites with probing depth (PD) ≥ 4 mm were treated by SRP using EGCG solution or distilled water as coolants respectively. Clinical parameters and red complex pathogens in the subgingival microbiome were evaluated at baseline, 3, and 6 months after treatments.

It was seen that during 6 months, the SRP plus EGCG medication contributed to additional PD reduction as 0.33 mm and gain of clinical attachment level as 0.3 mm compared with SRP alone, an approximate 8% more sites obtained PD reduction ≥ of 2 mm (p < 0.05). Meanwhile, the mean relative abundance of Tannerella forsythia was significantly lower in the combined treatment group (p < 0.05).

Hence, the authors concluded that "the purified EGCG showed the potential to improve the outcome of non-surgical periodontal treatment and the new-type scaler tip provided an alternative vehicle for subgingival medication."


Epigallocatechin gallatescaler tipscaling and root planingvehiclesubgingival medicationBMC Oral Health Journal
Source : BMC Oral Health Journal
Dr. Nandita Mohan
Dr. Nandita Mohan

    Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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