Single injection of botulinum neurobotulinum in masseter muscle tied to reversible maximal voluntary bite force reduction

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2023-06-16T20:00:36+05:30 | Updated On 17 Jun 2023 12:27 PM IST

Single intervention of 50units of botulinum neurotoxin in masseter muscle results in a reversible maximal voluntary bite force (MVBF) reduction of at least 3 months suggests a new study published in the Journal of Oral Rehabilitation.

Previous studies concerning the effect of botulinum toxin in masseter muscle have mainly reported effects observed through inspection of facial features or differences in pain levels. One systematic review of studies utilizing objective measurements reported that long-term muscular effect of botulinum neurotoxin injections into masseter muscle was inconclusive.

A study was done to evaluate the duration of reduced maximal voluntary bite force (MVBF) after botulinum toxin intervention.

The intervention group was comprised of individuals seeking aesthetic treatment for masseter reduction (n = 20), the reference group (n = 12) comprised of individuals with no intervention. Intervention through 25 units of Xeomin® (Merz Pharma GmbH & Co KGaA, Frankfurt am Main, Germany) botulinum neurotoxin type A injected into the masseter muscles bilaterally (totalling 50 units). A reference group did not receive any intervention. MVBF was measured in Newtons using a strain gauge meter at the incisors and first molars. MVBF was measured at baseline, at 4 weeks, 3 months, 6 months, and after 1 year.

Results

Both groups were similar in terms of bite force, sex and age at baseline. MVBF remained similar compared to baseline in the reference group. At 3 months, a significant reduction at all measurement points was observed in the intervention group; at 6 months, this reduction was no longer significant.

A single intervention of 50 units of botulinum neurotoxin results in a reversible maximal voluntary bite force (MVBF) reduction of at least 3 months, although a visually discernable reduction may be more long-lasting.

Reference:

Ågren, M, Nanchaipruek, Y, Phumariyapong, P, et al. Duration of bite force reduction following a single injection of botulinum toxin in the masseter muscle bilaterally: A one-year non-randomized trial. J Oral Rehabil. 2023; 50: 343- 350. doi:10.1111/joor.13434

Keywords:

Ågren, M, Nanchaipruek, Y, Phumariyapong, P, Duration, bite, force, reduction, following, single, injection, botulinum, toxin, masseter, muscle, bilaterally, one-year non-randomized, trial, J Oral Rehabil, Journal of Oral Rehabilitation

Journal of Oral Rehabilitationsingleintervention50 unitsbotulinumneurotoxinresultsreversibleMVBFreductionat least 3 month

Source : Journal of Oral Rehabilitation

Dr. Shravani Dali

Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751