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  • Topical human platelet...

Topical human platelet extract and vitamin C both help rejuvenate skin on the dorsal hands: Study

Written By : Jacinthlyn Sylvia |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2024-11-21T04:45:27+05:30  |  Updated On 21 Nov 2024 5:50 AM IST
Topical human platelet extract and vitamin C both help rejuvenate skin on the dorsal hands: Study
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A new study published in the journal of Plastic and Reconstructive Surgery showed that after using the human platelet extract (HPE) and vitamin C twice a day for 12 to 26 weeks were able to revitalize the skin on the dorsal hands. Traditionally, the face has been the primary target of topical skin-rejuvenating therapies, while the hands and other visible body parts have received less attention. Skin photoaging can be corrected using a variety of efficient therapies.

Topical human platelet extract (HPE) and topical L-ascorbic acid (vitamin C), a well-known antioxidant, are new off-the-shelf cosmetic ingredients that have demonstrated promising outcomes in recent clinical trials. HPE is a leukocyte-depleted allogeneic product made from pooled, apheresed platelets imported from the United States. In order to determine how topical HPE (plated) intense serum (Rion Aesthetics) and vitamin C (C E Ferulic with 15% L-ascorbic acid) affected the skin renewal of dorsal hands after 12 to 26 weeks of twice-daily use, Saranya Wyles and her team carried out this study.

This prospective, long-term study used photographic documentation was used at baseline, 6, 12, and 26-week evaluations to evaluate typical aging-related skin issues. The primary finding of this study was found that at 12 weeks following twice-daily topical application, topical HPE was not inferior to topical vitamin C for improving the fractional areas of wrinkles, brown spots, and luminosity on the dorsal hands. Despite their different function, vitamin C and HPE were both useful skin-rejuvenation therapies.

While vitamin C serves as an antioxidant and free radical seeker, protecting cells from oxidative stress, HPE offers other benefits for skin rejuvenation, including angiogenesis, collagen formation, and inflammatory management. Both compounds in a topical serum, brighten and level out skin tone while reducing photoaging symptoms including wrinkles, erythema, and brown spots when applied consistently as part of a skin care regimen. Only 50% of the overall sample population completed the research between 12 and 26 weeks, and there were few darker skin types (8% Fitzpatrick IV or V, 0 type VI), as well as a limited number of men. Overall, after 12 to 26 weeks of twice-daily topical use, HPE is equally effective as vitamin C to rejuvenate the skin on the dorsal hands.

Source:

Wyles, S., Jankov, L. E., Copeland, K., Bucky, L. P., Paradise, C., & Behfar, A. (2023). A Comparative Study of Two Topical Treatments for Photoaging of the Hands. In Plastic & Reconstructive Surgery (Vol. 154, Issue 5, pp. 978–984). Ovid Technologies (Wolters Kluwer Health). https://doi.org/10.1097/prs.0000000000011240

Plastic and Reconstructive Surgeryhuman platelet extractvitamin C
Source : Plastic and Reconstructive Surgery
Jacinthlyn Sylvia
Jacinthlyn Sylvia

    Neuroscience Masters graduate

    Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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