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  • Venous Thromboembolism...

Venous Thromboembolism Risk Lower among Patients with atopic dermatitis

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2024-01-01T06:00:29+05:30  |  Updated On 1 Jan 2024 6:00 AM IST
Venous Thromboembolism Risk Lower among Patients with atopic dermatitis
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Venous thromboembolism risk is lower among atopic dermatitis patients versus other immune-mediated inflammatory diseases suggests a new study published in the Journal of the American Academy of Dermatology.

Certain immune-mediated inflammatory diseases (IMIDs) may increase patients’ risk for venous thromboembolisms (VTEs), yet how atopic dermatitis (AD) influences VTE risk remains unclear. Describe venous thromboembolism incidence in patients with atopic dermatitis compared with other IMIDs and unaffected, atopic dermatitis-matched controls. This retrospective, observational, comparative cohort study used Optum® Clinformatics® United States claims data (2010–2019) of adults with atopic dermatitis, rheumatoid arthritis (RA), Crohn’s disease (CD), ulcerative colitis (UC), psoriasis (PsO), psoriatic arthritis (PsA), or ankylosing spondylitis (AS). Unaffected control patients were matched 1:1 with patients with atopic dermatitis. Results: Of 2,061,222 patients with IMIDs, 1,098,633 had atopic dermatitis. Patients with atopic dermatitis had a higher venous thromboembolism incidence (95% CI) than unaffected, atopic dermatitis-matched controls. However, when controlling for baseline VTE risk factors, atopic dermatitis was not associated with increased venous thromboembolism risk. Venous thromboembolism risk was lower in patients with atopic dermatitis versus RA, UC, CD, AS, or PsA; venous thromboembolism risk was similar in patients with psoriasis. atopic dermatitis did not increase venous thromboembolism risk when accounting for underlying risk factors. Atopic dermatitis was associated with lower venous thromboembolism risk compared with several rheumatologic and gastrointestinal IMIDs.

Reference: Joseph F. Merola, Brennan Ertmer, Huifang Liang, Xiaomeng Yue, Sarah Ofori, Whitney Krueger. Venous thromboembolism risk is lower in patients with atopic dermatitis than other immune-mediated inflammatory diseases: A retrospective, observational, comparative cohort study using US claims data, Journal of the American Academy of Dermatology, 2023, ISSN 0190-9622. https://doi.org/10.1016/j.jaad.2023.12.027.

(https://www.sciencedirect.com/science/article/pii/S019096222303400X)

Keywords: VTE, risk, lower, among, atopic, dermatitis, patients, versus, other, immune-mediated, inflammatory, diseases, Journal of the American Academy of Dermatology, Joseph F. Merola, Brennan Ertmer, Huifang Liang, Xiaomeng Yue, Sarah Ofori, Whitney Krueger, atopic dermatitis; cohort study; immune-mediated inflammatory disease; observational study; vascular disease; venous thromboembolism
VTEriskloweramongatopicdermatitispatientsversusotherimmune-mediatedinflammatorydiseasesThe Journal of the American Academy of Dermatology
Source : Journal of the American Academy of Dermatology
Dr. Shravani Dali
Dr. Shravani Dali

    Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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