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Gestational diabetes early in pregnancy tied to risk of postpartum glucose intolerance, finds study

Written By : Dr. Shravani Dali |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2024-12-25T21:45:00+05:30  |  Updated On 26 Dec 2024 11:26 AM IST
Gestational diabetes early in pregnancy tied to risk of  postpartum glucose intolerance,  finds study
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Gestational diabetes early in pregnancy tied to risk of postpartum glucose intolerance finds a study published in the Journal of Diabetes Investigation.

A study was done to compare perinatal outcomes and postpartum glucose tolerance between women diagnosed with gestational diabetes mellitus (GDM) before 20 weeks of gestation (EGDM) and those diagnosed at or after 24 weeks of gestation (LGDM) in a Japanese population.

Data were obtained from a prospective GDM registry. Multivariate analysis was conducted to examine the association between the timing of GDM diagnosis (EGDM vs LGDM) and perinatal outcomes (preterm birth, small for gestational age, large for gestational age, pregnancy-induced hypertension, and neonatal hypoglycemia), as well as postpartum glucose intolerance. Results: A total of 1,275 mother-infant pairs were analyzed for perinatal outcomes.

Of these, 924 women underwent postpartum testing for glucose intolerance. No significant differences in perinatal outcomes were observed between the EGDM and LGDM groups, except that overweight/obese women with EGDM had 2.5-fold higher rate of preterm birth than those with LGDM.

Postpartum glucose intolerance was 1.5 times more likely in the EGDM group than in the LGDM group. Women with EGDM had a significantly higher risk of postpartum glucose intolerance than those with LGDM, despite similar perinatal outcomes between the two groups.

Reference:

Yokoyama M, Miyakoshi K, Iwama N, Yamashita H, Yasuhi I, Kawasaki M, Arata N, Sato S, Imura Y, Waguri M, Kawaguchi H, Masaoka N, Nakajima Y, Hiramatsu Y, Sugiyama T; DREAMBee Study Gestational Diabetes Mellitus Group. Gestational diabetes in early pregnancy is associated with postpartum glucose intolerance: A perspective from the diabetes and pregnancy outcome for mother and baby study in Japan. J Diabetes Investig. 2024 Nov 28. doi: 10.1111/jdi.14368. Epub ahead of print. PMID: 39610144.

Gestationaldiabetesearlypregnancytiedriskpostpartumglucoseintolerancefinds study
Source : Journal of Diabetes Investigation
Dr. Shravani Dali
Dr. Shravani Dali

    Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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