Gestational diabetes mellitus not tied to increased all-cause mortality

Written By : Jacinthlyn Sylvia |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2024-02-13T10:45:54+05:30 | Updated On 13 Feb 2024 12:27 PM IST

A recent prospective cohort study investigated the potential link between the gestational diabetes mellitus (GDM) and long-term mortality. The major highlights of this study were published in the BMC Cardiovascular Diabetology.

This study was conducted from October 2022 to April 2023 and involved a total of 10,327 women with a pregnancy history to discern whether GDM, without subsequent overt diabetes, had any significant association with all-cause and cardiac mortality. The findings revealed critical insights into the health outcomes of women with a history of GDM. 5.3% of the participants had GDM alone, while 14.1% had overt diabetes. 758 deaths were recorded over a median follow-up period of 6.7 years.

This crucial findings of this study uncovered that GDM alone did not increase the risk of either all-cause or cardiac mortality. The participants in the GDM group showed comparable mortality rates to those without diabetes. Also, the group with overt diabetes faced a significantly higher risk of both all-cause and cardiac mortality when compared to their counterparts without diabetes.

The sensitivity analysis focused on women aged 50 or above and reinforced these findings. Among this subgroup, a history of GDM did not show any association with increased mortality risks. Overt diabetes remained significantly linked to heightened all-cause and cardiac mortality rates.

These findings challenge previous assumptions regarding the long-term health implications of gestational diabetes. While overt diabetes poses substantial risks, this research suggests that GDM alone may not contribute to the heightened mortality rates. These insights underscore the importance of distinguishing between different forms of diabetes and their respective impacts on long-term health outcomes.

Source:

Ying, Q., Xu, Y., Zhang, Z., Cai, L., Zhao, Y., & Jin, L. (2024). Gestational diabetes mellitus and risk of long-term all-cause and cardiac mortality: a prospective cohort study. In Cardiovascular Diabetology (Vol. 23, Issue 1). Springer Science and Business Media LLC. https://doi.org/10.1186/s12933-024-02131-3

BMC Cardiovascular Diabetologygestational diabetes mellitusall-cause mortality

Source : BMC Cardiovascular Diabetology

Jacinthlyn Sylvia

Neuroscience Masters graduate

Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751