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  • High-protein diet plan...

High-protein diet plan tied to lower blood sugar variability in Type 1 diabetes: Study

Written By : Dr Satabdi Saha |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2021-05-12T11:30:28+05:30  |  Updated On 12 May 2021 1:26 PM IST
High-protein diet plan tied to lower blood sugar variability in Type 1 diabetes: Study
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Compared with a 'standard' or 'reference' diet and a Mediterranean style diet (MED), a high-protein/low-carbohydrate diet (HPD) plan may have a positive impact on glycaemic control in patients with Type 1 diabetes (T1D), suggests findings from a recently published research in Diabetes, Obesity and Metabolism. The research has affirmed that during the high‐protein/low‐carbohydrate diet (HPD), patients spent a shorter time in hypoglycaemia and exhibited lower glycaemic variability.

The ideal dietary approach for patients with T1D diabetes, however, remains controversial, and the optimal macronutrient composition of the diet continues to be ambiguous. Most current guidelines do not generally distinguish between T1D and type 2 diabetes with regards to diet composition, and an individualized eating plan, based on a variety of dietary patterns that are acceptable for the management of diabetes, such as the Mediterranean style diet or a low‐carbohydrate diet is recommended.

Researchers undertook the current study to compare the effects of three different but isocaloric dietary patterns, high‐protein/low‐carbohydrate (HPD) with 20% of calories as carbohydrates, Mediterranean/low glycaemic index (MED) with 40% carbohydrates, and a reference diet (REF) with 50% carbohydrates, in patients with type 1 diabetes (T1D).

The study design consisted of a randomized crossover study, 15 patients with T1D were assigned to the three dietary patterns for three separate weeks, with 7‐day washout periods in between. Continuous glucose monitoring was applied during the intervention periods. The primary outcome was glycaemic control, as measured by the percentage of time patients spent within the euglycaemic range (TIR70–140 mg/dl). Other key glycaemic metrics were also investigated as secondary outcomes.

Data analysis highlighted some key facts.

• TIR70–140 was not statistically different between HPD, MED and REF (p = .105). Pairwise analysis revealed a statistically significant difference between HPD and REF at the .05 level, which was not retained after applying Bonferroni correction (54.87% ± 14.11% vs. 48.33% ± 13.72%; p = .018).

• During the HPD period, 11 out of 15 participants spent more time within TIR70–140 compared with either the REF or MED. The HPD performed significantly better than the REF in terms of TIR70–180 (74.33% ± 12.85% vs. 67.53% ± 12.73%; p = .012), glycaemic variability (coefficient of variation: 36.18% ± 9.30% vs. 41.48% ± 8.69%; p = .016) and time spent in the hypoglycaemic range (TBR70 mg/dl; median: 12, IQR: 16 vs. median: 14, IQR: 20; p = .007), whereas no statistically significant differences were observed between MED and HPD or REF.

The researchers concluded that compared with REF and MED, an High protein diet plan may have a positive impact on blood sugar control in patients with T1D. During the High protein diet plan (HPD), patients spent a shorter time in hypoglycaemia and exhibited lower blood sugar variability.

Primary source: Diabetes, Obesity and Metabolism

For full article follow the link: https://doi.org/10.1111/dom.14390

Type 1 diabetesglycemic controlDiabetes Obesity & Metabolismhigh protein low carbohydrate diet
Source : Diabetes, Obesity and Metabolism
Dr Satabdi Saha
Dr Satabdi Saha

    Dr Satabdi Saha (BDS, MDS) is a practicing pediatric dentist with a keen interest in new medical researches and updates. She has completed her BDS from North Bengal Dental College ,Darjeeling. Then she went on to secure an ALL INDIA NEET PG rank and completed her MDS from the first dental college in the country – Dr R. Ahmed Dental College and Hospital. She is currently attached to The Marwari Relief Society Hospital as a consultant along with private practice of 2 years. She has published scientific papers in national and international journals. Her strong passion of sharing knowledge with the medical fraternity has motivated her to be a part of Medical Dialogues.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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