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  • Long Term exposure to...

Long Term exposure to high-intensity outdoor light at night linked to Diabetes Prevalence

Written By : Dr.Niharika Harsha B |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2022-11-18T10:30:00+05:30  |  Updated On 18 Nov 2022 12:55 PM IST
Long Term exposure to high-intensity outdoor light at night linked to Diabetes Prevalence
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Researchers from China found that chronic exposure to higher-intensity outdoor Light at night (LAN) increases the prevalence of Diabetes due to an increased risk of impaired homeostasis. The study was published in the journal Diabetologia.

Diabetes is a global pandemic and out of the many risk factors, one of them is exposure to artificial light at night (LAN) as it might disrupt the circadian timing system. Hence researchers from China conducted a study called The China Noncommunicable Disease Surveillance Study. It was a national representative study conducted to estimate the associations of chronic exposure to outdoor LAN with glucose homeostasis markers and diabetes prevalence based on a national and cross-sectional survey of the general population in China in 2010.

Also Read: Long COVID-19 symptoms similar in hospitalized and nonhospitalized patients 2 years after infection: JAMA

From 162 study sites across mainland China, nearly 98,658 participants aged ≥18 years who had been living in their current residence for at least 6 months were recruited. Diabetes was defined as per the ADA criteria. Using the satellite data outdoor LAN exposure was estimated and the participants attending each study site were assigned the same mean radiance of the outdoor LAN at the study site. The relationships between LAN exposure and markers of glucose homeostasis were assessed using linear regression incorporating a restricted cubic spline function. Cox regression with a constant for the time variable assigned to all individuals and with robust variance estimates was used to assess the associations between the levels of outdoor LAN exposure and the presence of diabetes by calculating the prevalence ratios (PRs) with adjustment for age, sex, education, smoking status, drinking status, physical activity, family history of diabetes, household income, urban/rural areas, taking antihypertensive medications, taking lipid-lowering medications, and BMI.

Study findings:

  • The mean age of the study population was 42.7 years, and nearly 53,515 participants were women.
  • There were a positive correlation between outdoor LAN exposure levels and HbA1c, fasting and 2 h glucose concentrations, and HOMA-IR.
  • A negative association was found between outdoor LAN exposure and HOMA-B.
  • Diabetes prevalence was significantly associated with per-quintile LAN exposure (PR 1.07 [95% CI 1.02, 1.12]).
  • There was a significant association between the highest quintile of LAN exposure and an increased prevalence of diabetes compared with the lowest quintile of exposure.
Also Read: Long-term physical and mental health outcomes after COVID-19 occur in all ages

Thus, the present study shows evidence that LAN is detrimental to health, and it is a potential novel risk factor for diabetes due to the increased risk of impaired glucose homeostasis with chronic exposure to LAN.

Further reading: https://doi.org/10.1007/s00125-022-05819-x

Zheng, R., Xin, Z., Li, M. et al. Outdoor light at night in relation to glucose homeostasis and diabetes in Chinese adults: a national and cross-sectional study of 98,658 participants from 162 study sites. Diabetologia (2022).

artificial lightlight at nightcircadian timingdiabetesglucose homoeostasisdiabetes prevalenceHbA1c2 h glucose concentrations
Source : Diabetologia
Dr.Niharika Harsha B
Dr.Niharika Harsha B

    BDS, MDS

    Dr.Niharika Harsha B (BDS,MDS) completed her BDS from Govt Dental College, Hyderabad and MDS from Dr.NTR University of health sciences(Now Kaloji Rao University). She has 4 years of private dental practice and worked for 2 years as Consultant Oral Radiologist at a Dental Imaging Centre in Hyderabad. She worked as Research Assistant and scientific writer in the development of Oral Anti cancer screening device with her seniors. She has a deep intriguing wish in writing highly engaging, captivating and informative medical content for a wider audience. She can be contacted at editorial@medicaldialogues.in.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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