- Home
- Medical news & Guidelines
- Anesthesiology
- Cardiology and CTVS
- Critical Care
- Dentistry
- Dermatology
- Diabetes and Endocrinology
- ENT
- Gastroenterology
- Medicine
- Nephrology
- Neurology
- Obstretics-Gynaecology
- Oncology
- Ophthalmology
- Orthopaedics
- Pediatrics-Neonatology
- Psychiatry
- Pulmonology
- Radiology
- Surgery
- Urology
- Laboratory Medicine
- Diet
- Nursing
- Paramedical
- Physiotherapy
- Health news
- Fact Check
- Bone Health Fact Check
- Brain Health Fact Check
- Cancer Related Fact Check
- Child Care Fact Check
- Dental and oral health fact check
- Diabetes and metabolic health fact check
- Diet and Nutrition Fact Check
- Eye and ENT Care Fact Check
- Fitness fact check
- Gut health fact check
- Heart health fact check
- Kidney health fact check
- Medical education fact check
- Men's health fact check
- Respiratory fact check
- Skin and hair care fact check
- Vaccine and Immunization fact check
- Women's health fact check
- AYUSH
- State News
- Andaman and Nicobar Islands
- Andhra Pradesh
- Arunachal Pradesh
- Assam
- Bihar
- Chandigarh
- Chattisgarh
- Dadra and Nagar Haveli
- Daman and Diu
- Delhi
- Goa
- Gujarat
- Haryana
- Himachal Pradesh
- Jammu & Kashmir
- Jharkhand
- Karnataka
- Kerala
- Ladakh
- Lakshadweep
- Madhya Pradesh
- Maharashtra
- Manipur
- Meghalaya
- Mizoram
- Nagaland
- Odisha
- Puducherry
- Punjab
- Rajasthan
- Sikkim
- Tamil Nadu
- Telangana
- Tripura
- Uttar Pradesh
- Uttrakhand
- West Bengal
- Medical Education
- Industry
Paternal Diabetes Has No Significant Impact on Pregnancy Success Rates, Study Reveals
Denmark: A nationwide study has shed new light on the impact of paternal diabetes mellitus on pregnancy outcomes, revealing significant insights into reproductive health. Conducted across a diverse cohort undergoing reproductive treatments, the research offers a comprehensive analysis of how paternal health conditions, specifically diabetes, influence the success of pregnancies.
The cohort study analyzing 101,875 embryo transfers found that paternal diabetes mellitus does not markedly reduce the likelihood of achieving a successful pregnancy outcome.
"For paternal type 1 diabetes (T1D), the adjusted odds ratios for biochemical pregnancy, clinical pregnancy & live birth were 0.97, 1.08, and 0.75, respectively. For type 2 diabetes (T2D), the odds ratios were 0.80, 0.67, and 1.03, and for mixed-type diabetes, 0.95, 1.31, and 1.19," the researchers reported in Andrology Journal.
Approximately 15% of all pregnancies result in pregnancy loss. While most research has concentrated on maternal factors, there is limited understanding of how paternal factors impact the likelihood of a successful pregnancy. To fill this knowledge gap, Anne-Sofie Sønnichsen-Dreehsen, Center for Clinical Epidemiology, Odense University Hospital, Odense, Denmark, and colleagues aim to evaluate the chance of clinical pregnancy, biochemical pregnancy, and live-born children in couples where the male partner has diabetes mellitus (DM).
For this purpose, the researchers performed a nationwide cohort study. It included couples undergoing assisted reproductive technology treatment from 2006 to 2019. he exposed cohorts comprised embryo transfers in couples with paternal T1DM, T2DM, or mixed type DM (TMDM).
The exposed cohorts comprised embryo transfers in couples with paternal type 1 DM (T1DM), type 2 DM (T2DM), or mixed type DM (TMDM). The unexposed cohort included embryo transfers in couples without paternal DM.
The following were the key findings of the study:
- A total of 101,875 embryo transfers were included. Of these, 503 males had T1DM, 225 males had T2DM, 263 males had TMDM, and 100,884 did not have DM.
- For paternal T1DM, the adjusted OR for achieving a biochemical pregnancy, clinical pregnancy, and live-born child were 0.97, 1.08, and 0.75, respectively.
- For paternal T2DM, the adjusted OR for achieving a biochemical pregnancy, clinical pregnancy, and live-born child were 0.80, 0.67, and 1.03, respectively.
- For the paternal TMDM, the adjusted OR for achieving a biochemical pregnancy, clinical pregnancy, and livebirth were 0.95, 1.31, and 1.19, respectively.
The study found that paternal diabetes mellitus did not reduce the likelihood of achieving pregnancy or having a live-born child compared to couples without paternal diabetes.
"While these results are reassuring, further research is needed to confirm these findings. Future studies should include data on male lifestyle factors, such as smoking and alcohol use, as well as clinical parameters like the severity and management of diabetes, before drawing definitive conclusions," the researchers concluded.
Reference:
Sønnichsen-Dreehsen, S., Fedder, J., Wod, M., Thorarinsson, C. T., & Nørgård, B. M. The association between paternal diabetes mellitus and successful pregnancy—Examined in a nationwide population undergoing reproductive treatment. Andrology. https://doi.org/10.1111/andr.13702
MSc. Biotechnology
Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at  editorial@medicaldialogues.in. Contact no. 011-43720751
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751