- Home
- Medical news & Guidelines
- Anesthesiology
- Cardiology and CTVS
- Critical Care
- Dentistry
- Dermatology
- Diabetes and Endocrinology
- ENT
- Gastroenterology
- Medicine
- Nephrology
- Neurology
- Obstretics-Gynaecology
- Oncology
- Ophthalmology
- Orthopaedics
- Pediatrics-Neonatology
- Psychiatry
- Pulmonology
- Radiology
- Surgery
- Urology
- Laboratory Medicine
- Diet
- Nursing
- Paramedical
- Physiotherapy
- Health news
- AYUSH
- State News
- Andaman and Nicobar Islands
- Andhra Pradesh
- Arunachal Pradesh
- Assam
- Bihar
- Chandigarh
- Chattisgarh
- Dadra and Nagar Haveli
- Daman and Diu
- Delhi
- Goa
- Gujarat
- Haryana
- Himachal Pradesh
- Jammu & Kashmir
- Jharkhand
- Karnataka
- Kerala
- Ladakh
- Lakshadweep
- Madhya Pradesh
- Maharashtra
- Manipur
- Meghalaya
- Mizoram
- Nagaland
- Odisha
- Puducherry
- Punjab
- Rajasthan
- Sikkim
- Tamil Nadu
- Telangana
- Tripura
- Uttar Pradesh
- Uttrakhand
- West Bengal
- Medical Education
- Industry
Probiotic supplementation may benefit patients with prediabetes, diabetes or gestational diabetes
![Probiotic supplementation may benefit patients with prediabetes, diabetes or gestational diabetes Probiotic supplementation may benefit patients with prediabetes, diabetes or gestational diabetes](https://medicaldialogues.in/h-upload/2021/03/12/750x450_150182-probiotics-1.webp)
China: The supplementation of probiotic/prebiotic/synbiotic may improve blood sugar profile among patients with type 2 diabetes/gestational diabetes, gestational women with normal glucose, or people with prediabetes, according to results from a meta-analysis published in Public Health.
Previous studies have investigated the effects of probiotic/prebiotic/synbiotic supplementation on blood glucose profiles in patients with diabetes. However, the results have not been consistent.
Considering the above, Z. Wang, Tianjin Medical University, Tianjin, China, and colleagues conducted a systematic search from online databases (PubMed, Embase, ISI Web of Science, and Cochrane Central) to identify high-quality clinical trials examining the effect of probiotic/prebiotic/synbiotic supplementation on blood glucose profiles [including hemoglobin A1c (HbA1c), fasting blood glucose (FBG), and homeostasis model assessment of insulin resistance (HOMA-IR)] up to December 2020. To investigate the different effects among different populations, subgroup analyses by types or durations of probiotic/prebiotic/synbiotic supplementation were conducted. The final analyses included a total of 39 trials with 3517 participants.
Based on the study, the researchers reported the following:
- Among patients with type 2 diabetes (T2DM), the summarized standardized mean differences (SMDs) of FBG, HbA1c, and HOMA-IR were −0.30, −0.59, and −0.68, respectively.
- Among patients with gestational diabetes (GDM), the summary SMDs of FBG, HbA1c, and HOMA-IR were −0.67, −0.24, and −1.06, respectively.
- Similar improvements in blood glucose profiles were also found among persons with prediabetes or gestational woman with normal glucose, but not among patients with type I diabetes.
- Subgroup analyses showed similar results for probiotic supplementation for patients with T2DM and probiotic/synbiotic supplementation for patients with GDM.
"In patients with type 2 diabetes/gestational diabetes, persons with prediabetes, or gestational women with normal glucose, probiotic/prebiotic/synbiotic supplementation might improve the blood glucose profiles," the researchers wrote. "There is a need for trials with more sophisticated design to validate the results in the future."
Reference:
Wang, Z, et al. "Effects of Probiotic/prebiotic/synbiotic Supplementation On Blood Glucose Profiles: a Systematic Review and Meta-analysis of Randomized Controlled Trials." Public Health, vol. 210, 2022, pp. 149-159.
MSc. Biotechnology
Medha Baranwal joined Medical Dialogues as an Editor in 2018 for Speciality Medical Dialogues. She covers several medical specialties including Cardiac Sciences, Dentistry, Diabetes and Endo, Diagnostics, ENT, Gastroenterology, Neurosciences, and Radiology. She has completed her Bachelors in Biomedical Sciences from DU and then pursued Masters in Biotechnology from Amity University. She has a working experience of 5 years in the field of medical research writing, scientific writing, content writing, and content management. She can be contacted at  editorial@medicaldialogues.in. Contact no. 011-43720751
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: editorial@medicaldialogues.in. Contact no. 011-43720751