Troponin and D-dimer significant predictors of pulmonary embolism in T2DM, reveals study
Type 2 diabetes mellitus (T2DM) is a condition characterized by a prothrombotic, proinflammatory, and hypofibrinolytic state. However, the relationship between T2DM and pulmonary embolism (PE) remains unclear. PE is a common cardiovascular disease that can have serious clinical consequences. Despite this, many patients at risk for PE are not identified in routine clinical practice.
- T2DM patients showed elevated troponin, D-dimer, CRP, uric acid, fibrinogen, and HOMA-IR, and they experienced more severe complications and higher mortality rates within ten days of hospital admission.
- Significant predictors of PE in T2DM patients were found. Troponin and D-dimer were significant predictors of PE in type 2 diabetes mellitus. These patients also had significantly higher waist circumference and BMI.
- PE patients with T2DM had higher total cholesterol, LDL cholesterol, triglycerides, and glucose and lower HDL cholesterol.
- PE patients with T2DM had a 4.38 times higher chance of death compared to those with pulmonary embolism without T2DM.
The results show notable associations and point to potential risk factors for these patient populations. Our findings suggest that measuring troponin values in patients with pulmonary embolism and T2DM could help distinguish high- and intermediate-risk patients from low-risk ones, in line with previous studies. This could make troponin a valuable tool for risk assessment and early detection of PE in this group.
