- Home
- Medical news & Guidelines
- Anesthesiology
- Cardiology and CTVS
- Critical Care
- Dentistry
- Dermatology
- Diabetes and Endocrinology
- ENT
- Gastroenterology
- Medicine
- Nephrology
- Neurology
- Obstretics-Gynaecology
- Oncology
- Ophthalmology
- Orthopaedics
- Pediatrics-Neonatology
- Psychiatry
- Pulmonology
- Radiology
- Surgery
- Urology
- Laboratory Medicine
- Diet
- Nursing
- Paramedical
- Physiotherapy
- Health news
- AYUSH
- State News
- Andaman and Nicobar Islands
- Andhra Pradesh
- Arunachal Pradesh
- Assam
- Bihar
- Chandigarh
- Chattisgarh
- Dadra and Nagar Haveli
- Daman and Diu
- Delhi
- Goa
- Gujarat
- Haryana
- Himachal Pradesh
- Jammu & Kashmir
- Jharkhand
- Karnataka
- Kerala
- Ladakh
- Lakshadweep
- Madhya Pradesh
- Maharashtra
- Manipur
- Meghalaya
- Mizoram
- Nagaland
- Odisha
- Puducherry
- Punjab
- Rajasthan
- Sikkim
- Tamil Nadu
- Telangana
- Tripura
- Uttar Pradesh
- Uttrakhand
- West Bengal
- Medical Education
- Industry
TyG-BMI Emerges as Potential Diagnostic Index for Hypertension
![TyG-BMI Emerges as Potential Diagnostic Index for Hypertension TyG-BMI Emerges as Potential Diagnostic Index for Hypertension](https://medicaldialogues.in/h-upload/2023/05/10/750x450_209234-insulin.webp)
Hypertension, continues to be a prevalent health concern worldwide. The interplay between insulin resistance (IR), obesity, and hypertension has been the focus of numerous research studies. In a recent investigation, Hamid Reza Nikbakht and team explored the connection between the triglyceride-glucose body mass index (TyG-BMI) and the risk of hypertension in adults.
The study, which involved 8,610 participants from the baseline phase of the Ravansar non-communicable diseases (RaNCD) project in Iran, utilized a logistic regression model to assess the relationship between TyG-BMI and hypertension. Additionally, the researchers employed Receiver Operating Characteristic (ROC) curve analysis to determine the predictive power of TyG-BMI concerning hypertension.
The findings revealed that among the participants, consisting of 4,176 men and 4,434 women with an average age of 46.74 years, anthropometric indices were significantly higher in those with hypertension compared to normotensive individuals (P < 0.001). Interestingly, physical activity levels were notably higher in the bottom quartiles (P < 0.001).
Regarding the TyG-BMI index, the study unveiled a significant association with hypertension risk. The odds of developing hypertension were 3.10 times higher (95% CI: 2.28, 4.16) in individuals belonging to the highest TyG-BMI quartile compared to those in the bottom quartile. This observation suggests that TyG-BMI may serve as a potential indicator for early diagnosis of hypertension.
The ROC curve analysis demonstrated that the discriminating ability of TyG-BMI in predicting blood pressure was 61% (AUC: 0.61; 95% CI: 0.57, 0.63), which was higher than BMI and TyG alone. This highlights the potential value of incorporating the TyG-BMI index in assessing hypertension risk more accurately.
The link between hypertension and insulin resistance as well as obesity has been established in various studies. Notably, TyG is considered a reliable surrogate marker for insulin resistance. Therefore, the combination of TyG with BMI appears to offer valuable insights into the risk of hypertension in adults.
The researchers emphasized the importance of lifestyle modifications in managing insulin resistance, obesity, and ultimately preventing hypertension. Weight control through regular physical activity and a healthy diet was recommended as an effective approach to improve insulin resistance and reduce the risk of hypertension.
Source:
Nikbakht, H. R., Najafi, F., Shakiba, E., Darbandi, M., Navabi, J., & Pasdar, Y. (2023). Triglyceride glucose-body mass index and hypertension risk in iranian adults: a population-based study. In BMC Endocrine Disorders (Vol. 23, Issue 1). Springer Science and Business Media LLC. https://doi.org/10.1186/s12902-023-01411-5
Neuroscience Masters graduate
Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: editorial@medicaldialogues.in. Contact no. 011-43720751