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  • Microscopic colitis...

Microscopic colitis patients prone to higher risk of acute pancreatitis

Written By : Aditi |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2023-05-22T20:00:52+05:30  |  Updated On 22 May 2023 8:00 PM IST
Microscopic colitis patients prone to higher risk of acute pancreatitis
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Sweden: A study published in The American Journal of Gastroenterology, entitled "Microscopic colitis and risk of incident acute pancreatitis: A nationwide population-based matched cohort study" by Bergman et al. and colleagues have demonstrated that patients with microscopic colitis or MC have a higher risk of acute pancreatitis.

It is already known that there is an association between gastrointestinal diseases and acute pancreatitis. There is a lack of data regarding acute pancreatitis risk in microscopic colitis.

Considering this background, researchers did a matched cohort study in 12,140 patients with biopsy-verified MC (diagnosed in 2003-2017), 57,806 matched reference individuals, and 12,781 siblings without MC with follow-up until 2021.

They obtained data from all of Sweden's regional pathology registers through the ESPRESSO cohort.

The study results could be summarised as follows:

  • The duration of the mean follow-up was 9.9 years.
  • The diagnosis of acute pancreatitis was established in 146 MC patients and 437 reference individuals with values of 127.8 vs 80.1 per 100,000 person-years.
  • There was a positive association between MC and acute non-gallstone-related pancreatitis.
  • There was no association with acute gallstone-related pancreatitis.

They said that, Based on our study's results, we found an elevated risk of acute pancreatitis for MC patients with a follow-up exceeding ten years.

They acknowledged, "The clinicians should have a low threshold for evaluating acute pancreatitis in patients with MC. It is important consideration that patients should receive advice and care to reduce acute pancreatitis risk.

Further reading:

Bergman, David MD, PhD1,a; Roelstraete, Bjorn PhD1; Olén, Ola MD, PhD2-4; Lindkvist, Björn MD, PhD5; Ludvigsson, Jonas F MD, PhD1,6-7. Microscopic colitis and risk of incident acute pancreatitis: A nationwide population-based matched cohort study. The American Journal of Gastroenterology ():10.14309/ajg.0000000000002318, May 12, 2023. | DOI: 10.14309/ajg.0000000000002318


The American Journal of Gastroenterology.microscopic colitisMCacute pancreatitis
Source : The American Journal of Gastroenterology
Aditi
Aditi

    BDS, MDS in Periodontics and Implantology

    Dr. Aditi Yadav is a BDS, MDS in Periodontics and Implantology. She has a clinical experience of 5 years as a laser dental surgeon. She also has a Diploma in clinical research and pharmacovigilance and is a Certified data scientist. She is currently working as a content developer in e-health services. Dr. Yadav has a keen interest in Medical Journalism and is actively involved in Medical Research writing.

    Dr. Kamal Kant Kohli
    Dr. Kamal Kant Kohli

    Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751

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