Optimal Vitamin D levels may help prevent development of non-alcoholic fatty liver disease

Written By : Jacinthlyn Sylvia |Medically Reviewed By : Dr. Kamal Kant Kohli Published On 2023-01-31T20:00:10+05:30 | Updated On 31 Jan 2023 8:00 PM IST

A recent study suggest the importance of maintaining optimal vitamin D levels to help prevent the development of steatosis in patients with non-alcoholic fatty liver disease (NAFLD). The findings of this study were published in the Journal of Endokrynologia Polska.

Vitamin D is a crucial nutrient that has a range of health benefits, including its role in maintaining healthy bones and overall immune system function. However, its impact on steatosis, a condition characterized by the buildup of excess fat in the liver, has not been fully explored. In this study, researchers aimed to examine the relationship between vitamin D status and steatosis in a large-scale population-based cohort.

The study included patients diagnosed with either simple steatosis or non-alcoholic steatohepatitis (NASH), who had 25-hydroxyvitamin D (25OHD) measurements at the time of their diagnosis. A control group was also included, consisting of subjects without liver diseases. The study recorded age, gender, 25OHD levels, and alanine aminotransferase (ALT) levels.

The key highlights of the study were:

25OHD levels were lower and ALT levels were higher in the patient group compared to the control group. Logistic regression analysis revealed that a decrease in 25OHD levels by 1 ng/dL increased the risk of being in the patient group by 3.7%.

In conclusion, the results from this study suggest that there may be a weak relationship between vitamin D status and the development of non-alcoholic fatty liver disease (NAFLD). Further research is required to fully understand this relationship and its potential implications for the prevention and treatment of NAFLD.

Source:

Dal, K., Uzman, M., Ata, N., Ertugrul, D. T., Bursa, N., Caglayan, M., Baser, S., Akkan, T., Imrat, E., Celik, O., Ulgu, M. M., Sahin, M., & Birinci, S. (2023). The effect of vitamin D status on non-alcoholic fatty liver disease: a population-based observational study. In Endokrynologia Polska. VM Media SP. zo.o VM Group SK. https://doi.org/10.5603/ep.a2023.0002

Endokrynologia Polskavitamin Dnon-alcoholic fatty liver disease

Source : Endokrynologia Polska

Jacinthlyn Sylvia

Neuroscience Masters graduate

Jacinthlyn Sylvia, a Neuroscience Master's graduate from Chennai has worked extensively in deciphering the neurobiology of cognition and motor control in aging. She also has spread-out exposure to Neurosurgery from her Bachelor’s. She is currently involved in active Neuro-Oncology research. She is an upcoming neuroscientist with a fiery passion for writing. Her news cover at Medical Dialogues feature recent discoveries and updates from the healthcare and biomedical research fields. She can be reached at editorial@medicaldialogues.in

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751