Cefroxadine

Cefroxadine belongs to the pharmacological class of first-generation cephalosporin antibiotics. Cefroxadine, is the only oral antibiotic, is being experimented for the use against gram positive and gram negative bacteria.

Cefroxadine belongs to the pharmacological class of first-generation cephalosporin antibiotics. Cefroxadine, is the only oral antibiotic, is being experimented for the use against gram positive and gram negative bacteria.

Cefroxadine is a cephalosporin antibiotic, which belongs to the class of β-lactam antibiotics which are similar to penicillins, which binds to and inhibits penicillin binding proteins (PBPs).

The common side effects involving the use of Cefroxafine are nausea, vomiting, itching or irritation on the skin, stomach pain , mild diarrhea etc.

The following are the side effects involving Cefroxadine:

• Dizziness
• Feeling restless or hyperactive
• Unusual or unpleasant taste in your mouth
• Nausea
• Vomiting
• Stomach pain
• Mild diarrhea
• Stiff or tight muscles
• Joint pain
• Mild itching or skin rash
• Vaginal itching or discharge

Pharmacodynamics

Cefroxadine is said to be a cephalosporin antibiotic which produces a bactericidal effect on susceptible bacteria

Pharmacokinetics

• Absorption

Cefroxadine has oral bioavailability of 90% .

• Volume of distribution

Cefroxadine has a volume of distribution of 15 L .

• Protein binding

Cefroxadine is 10% bound to human plasma proteins .

• Metabolism

Not Available

• Route of elimination

Cefroxadine is primarily eliminated in the urine (80-96%)

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2. https://watsonshealth.com.ph/cefroxadine/#1503553275888-e54d33f9-1282
3. https://go.drugbank.com/drugs/DB11367
4. https://www.drugfuture.com/chemdata/Cefroxadine.html
5. https://www.medchemexpress.com/cefroxadine.html
6. https://drugs.ncats.io/drug/B908C4MV2R
7. https://pubchem.ncbi.nlm.nih.gov/compound/Cefroxadine