Dextrothyroxine

Dextrothyroxine is a Antilipemic Agents

Dextrothyroxine is used to lower high cholesterol levels in the blood.

Dextrothyroxine shows common side effects like weight loss, headache, abdominal pain, nausea

Dextrothyroxine is available in Tablet

Dextrothyroxine is available in India, Germany, Canada, France, USA.

Dextrothyroxine is a antihyperlipidemic. The mechanism of action is not completely understood, but Dextrothyroxine apparently acts in the liver to stimulate formation of low-density lipoprotein (LDL) and, to a much greater extent, to increase catabolism of LDL. This leads to increased excretion of cholesterol and bile acids via the biliary route into the feces, with a resulting reduction in serum cholesterol and LDL. Dextrothyroxine has no significant effect on high-density lipoproteins (HDL).

Dextrothyroxine is available in the form of tablets.

Dextrothyroxine is used to lower high cholesterol levels in the blood.

Dextrothyroxine stimulates low-density lipoprotein (LDL) formation in the liver and also increases its catabolic action. The drug increases bile and cholesterol excretion so that they are removed with the faeces and hence, LDL and serum cholesterol is reduced.

Dextrothyroxine is approved for use in the following clinical indications

Dextrothyroxine is indicated to lower high cholesterol levels in the blood.

Dextrothyroxine is available in the form of Tablets.

Take after eating and with a full glass of water to decrease gastric upset.

Common Adverse effects:

• Headache
• Flushing
• Indigestion

Less Common Adverse effects:

• Serious allergic reaction which causes difficulty in breathing or dizziness
• Difficulty in breathing or wheezing
• Nausea (feeling sick)
• Rash, itching, redness
• Inflammation of muscle tissue causing pain in the muscles and joints
• Feeling hot, malaise (generally not feeling well)

Rare Adverse effects

• Eye problems including dry or gritty eye
• Vasodilatation (widening of the blood vessels)
• Diarrhea

May enhance the myopathic (rhabdomyolysis) effect of statins and fibrates.

The common side effects of Dextrothyroxine include the following :

Headache

Flushing

Indigestion

• Pharmacodynamic

Dextrothyroxine is a antihyperlipidemic. The mechanism of action is not completely understood, but Dextrothyroxine apparently acts in the liver to stimulate formation of low-density lipoprotein (LDL) and, to a much greater extent, to increase catabolism of LDL. This leads to increased excretion of cholesterol and bile acids via the biliary route into the feces, with a resulting reduction in serum cholesterol and LDL. Dextrothyroxine has no significant effect on high-density lipoproteins (HDL).

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1364710/
• https://reference.medscape.com/drug/colestid-Dextrothyroxine -342452
• https://go.drugbank.com/drugs/DB00375
• https://www.sciencedirect.com/topics/medicine-and-dentistry/Dextrothyroxine
• https://europepmc.org/article/med/6988203