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OverviewMechanism of ActionUsesIndicationsMethod of AdministrationDosage StrengthsDosage FormsDietary RestrictionsContraindicationsWarnings and Precautions for usingOverdosage Clinical Pharmacology Authored by Reviewed by References
Theobromine

Theobromine

Indications, Uses, Dosage, Drugs Interactions, Side effects
Theobromine
Medicine Type :
Allopathy
Prescription Type:
Prescription Required
Approval :
Investigational Drug
Schedule
Schedule H
Pharmacological Class:
Methyl Xanthines,
Therapy Class:
Bronchodilator,

Theobromine belongs to the pharmacological class Methyl Xanthines. Theobromine appears to have bronchodilatory effects in the pulmonary system. Theobromine is rapidly mediated through competitive inhibition of phosphodiesterase, which in turn results in an increase in cyclic AMP, thereby produces relaxation of bronchial smooth muscle as well as antagonistic effect of adenosine receptors. Theobromine is being investigated for the reduction of asthma symptoms.

Theobromine belongs to the pharmacological class of Methyl Xanthines. Theobromine appears to have Bronchodilator effects. Theobromine is rapidly mediated through competitive inhibition of phosphodiesterase, which in turn results in an increase in cyclic AMP, thereby produces relaxation of bronchial smooth muscle as well as antagonistic effect of adenosine receptors. Theobromine is being investigated for the reduction of asthma symptoms.

Theobromine is being investigated for the reduction of asthma symptoms.

Theobromine is being investigated for the reduction of asthma symptoms.

Maintaining health and smoking cessation and is a must.

In take of Caffeine is to be avoided or limited to use as it may lead to the risk of nervousness, rapid heartbeat, nausea, palpitationsetc.

Alcohol should be avoided in the patient especially in pateints with an underlying liver disorder or liver dysfunction

Diet containing food with a salt, preservatives, refined and high energy-dense foods, high glycemic index, red and processed meat, added sugar, saturated and trans fat food, low fiber, low antioxidants, and vitamins is to be restricted.

The dietary restrictions should be individualized as per the patient's requirements.

Theobromine may be contraindicated under the following conditions:

  • Hypersensitivity to the ingredients of the medication

Alcohol Warning

Avoid alcohol usage while on Theobromine medication as alcohol can worsen the effects of any underlying disease condition, including conditions such as dizziness, blurred vision etc.

Breast Feeding Warning

Theobromine might be secreted in human milk. As there is potential for adverse reactions, which can be serious in nursing infants from use of Theobromine, hence a decision should be made whether to discontinue the drug or to discontinue nursing, taking into account the importance of the drug Theobromine to the mother.

Food Warning

No sufficient scientific evidence traceable regarding the use and safety of Theobromine in concurrent use with any particular food.

Physician should be vigilant and knowledgeable about the treatment pertaining to the identification and treatment of overdosage of Theobromine.

There has found to be no reports pertaining to the overdosage information related to Theobromine medication.

Pharmacodynamics

Theobromine, a xanthine derivative like caffeine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity).

  • https://go.drugbank.com/drugs/DB01412
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Sonali R Muralidhar
I am Sonali R Muralidhar currently residing at Madurai.I have completed my Master’s in Pharmacy with my core subject as Pharmaceutics. I am interested in Pharmaceutical research , medical content writing, Biopharmaceutics , regulatory affairs , novel drug delivery, targeted drug delivery.
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Dr JUHI SINGLA
Dr JUHI SINGLA has completed her MBBS from Era’s Lucknow Medical college and done MD pharmacology from SGT UNIVERSITY Gurgaon. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751
Published on: 23 Dec 2022 6:12 PM GMT
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