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Alkem Labs Launches Vonzai, the Next Generation Therapy for APD Management - Video

Published On 2024-10-01T11:15:03+05:30  |  Updated On 10 Oct 2024 5:29 PM IST
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Overview

Alkem Labs, one of the leaders in the gastro segment with well-known products like PAN, Pan-D, and Obetohep has announced the launch of the next-generation molecule, Vonoprazan in India under the brand name Vonzai. Vonzai will be launched under its newly established Gastrokem division. In a non-exclusive patent licensing with Takeda, Alkem aims to bring this novel treatment to the Indian market.

Vonzai tablets containing Vonoprazan are available in two dosage strengths: 10 mg and 20 mg. Vonoprazan fumarate has been approved by DCGI for the treatment of reflux esophagitis (RE), gastric ulcers and duodenal ulcers.

Studies indicate that P-CABs can help to bridge current therapeutic gaps through their longer half-life, greater effectiveness against nocturnal acid breakthrough and meal-independent dosing.

Unlike conventional therapies, P-CABs are acid-stable, do not require an enteric coating, and act immediately on proton pump, eliminating the need for pre-meal dosing. Vonoprazan is rapidly absorbed, reaching peak plasma concentration within two hours, and provides prolonged acid suppression1.

Speaking to Medical Dialogues about the launch, Dr Vikas Gupta, CEO Alkem labs said, "The increase in reflux and acid-peptic diseases, caused by modern diets and lifestyles, is a major concern. With the launch of Vonzai, Alkem’s foothold in the gastrointestinal market is set to grow even further. Vonoprazan’s novel mechanism of action will enable us to enhance treatment and provide much-needed relief for millions of patients facing gastro-related health challenges in India".

He also added, “Alkem’s strong presence in the GI segment, supported by its dedicated Gastrokem division and robust distribution network of Alkem, reinforces our commitment to improving patient care and outcomes. With the launch of Vonzai, we are taking a significant step forward in offering innovative treatment options for millions of patients suffering from GI disorders”.

Alkem Laboratories Limited, a global pharmaceutical company headquartered in Mumbai, India, specializes in the production and distribution of generic pharmaceuticals formulations, and nutraceuticals across both domestic and international markets.

Reference:

  1. Simadibrata DM, Syam AF, Lee YY. A comparison of efficacy and safety of potassium-competitive acid blocker and proton pump inhibitor in gastric acid-related diseases: A systematic review and meta-analysis. J Gastroenterol Hepatol. 2022 Dec;37(12):2217-2228. doi: 10.1111/jgh.16017.


Disclaimer: This post has been published under MD Brand Connect Initiative and is sponsored by Alkem Laboratories Limited.

Speakers

Dr. Nandita Mohan

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751
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