Clinical profile of patients with mural infective endocarditis vs valvular endocarditis - Video

Published On 2022-08-22T09:15:22+05:30 | Updated On 22 Aug 2022 9:15 AM IST

Overview

Infective endocarditis patients present very rarely with vegetations on the mural endocardium. There are very few studies that are available comparing Mural infective endocarditis with commoner valvular or device related infective endocarditis.

To analyse the clinical features, microbiological profile and clinical course of mural endocarditis in comparison to valvular endocarditis, the present study was published in Indian Heart Journal that revealed that mural endocarditis is equally riskier and fatal as that valvular endocarditis.

A retrospective analysis of data included Patients who were reported to have vegetations on the mural endocardial surface – these patients were taken as a group and compared with rest of the patients. Clinical profile, laboratory parameters including culture and outcomes were compared between the two groups.

Out of 278 patients in the study, 5.38% had vegetations on the mural endocardium. Of them, only 4 patients had structural heart diseases. Many aspects were compared between the two groups. It was found that ventricles were the commonest sites of vegetations. Inflammatory markers like ESR and CRP were low in mural endocarditis compared to rest. Culture positivity was high in mural endocarditis and Staphylococcus Aureus was the commonest organism. Mural endocarditis patients had similar in hospital mortality to rest of the patients. Cardiac complications were not reported in mural endocarditis, but they had similar incidence of embolic complications including neurological events.

So the researchers concluded that mural endocarditis is a rare clinical entity with similar morbidity and mortality to that of endocarditis with valvular vegetation.

Reference: Gopalan Nair Rajesh, Haridasan Vellani, et al; Clinical profile and one-year outcomes of patients with mural infective endocarditis: – A tertiary care centre study based on data from a seven-year registry, Indian Heart Journal, Volume 74, Issue 3,DOI:https://doi.org/10.1016/j.ihj.2022.05.003.

Speakers

Dr. Nandita Mohan

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751