COMBINE-Angina Study Explained: Expert Insights from Dr Abhishek Shukla - Video
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Overview
In this video, Dr Abhishek Shukla, Consultant Cardiologist at Ajanta Hospital, Lucknow, shares key insights from the COMBINE-Angina study - an international, prospective study evaluating the early addition of trimetazidine in patients with stable angina who remain symptomatic despite first-line hemodynamic therapy.
The study, published in the International Journal of Cardiology and presented at ESC Congress 2025, highlights the clinical value of combining metabolic and hemodynamic approaches in angina management. Dr Shukla discusses the real-world relevance of SAQ-7 score improvements, the impact on patients’ daily lives, and the applicability of these findings in Indian clinical practice. He also shares practical takeaways for cardiologists managing symptomatic stable angina.
Speakers
Dr Abhishek Kumar Shukla, MBBS, MD, DM (Cardiology), AFSCAL, FESC, is Head of the Interventional Cardiology Unit at Ajanta Hospital, Lucknow, and Consultant & Director at Pulse Heart Care, Indira Nagar, Lucknow. A gold medalist in MBBS (KGMU, Lucknow, 2007) and MD General Medicine (GSVM Medical College, Kanpur, 2011), he completed his DM in Cardiology from Rabindranath Tagore Medical College, Udaipur (2015). With over 10 years of experience in interventional cardiology, he has been a principal investigator in trials such as RECORD ACS and REOPEN and has multiple national and international publications. He is a member of the Cardiology Society of India and the Indian Medical Association and has performed over 15,000 interventional procedures, including complex angioplasty and advanced cardiac interventions.