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Intravascular lithotripsy in calcified coronaries in Indian patients safe?
Calcified coronaries still remain a major challenge for interventional cardiologist. The study that I am talking about published in the Indian Heart Journal aimed to evaluate safety and efficacy of intravascular lithotripsy (IVL) in management of coronary artery calcification.
A retrospective single center study included patients with hemodynamically stable acute coronary syndrome or symptomatic chronic coronary syndrome (CCS) and calcified coronaries on angiography. All those who underwent IVL were enrolled. The primary endpoint was procedural success.
A total of 29 patients underwent intravascular lithotripsy with a majority being males and having comorbidities such as hypertension and diabetes. The procedural success rate of 93.1% was achieved.
The arteries most commonly intervened were the left main coronary and the left anterior descending artery. Intracoronary imaging revealed a significant increase in minimum luminal cross-sectional area post intravascular lithotripsy. Two patients had in-hospital Major Adverse Carciac Events in form of peri- procedural non Q-wave Myocardial Infarction. No patient had arrhythmias, stent thrombosis, coronary perforation, or slow flow/no-reflow. Two patients had a rupture of IVL balloon while four had coronary artery dissection.
Researchers therefore, concluded that intravascular lithotripsy is a safe and highly effective modality with high procedural success rate in management of calcified coronaries.
Reference: Rao RS, Sharma GN, Kunal S, Garhwal K, Bajiya S, Mehta P. Safety and procedural outcomes of intravascular lithotripsy in calcified coronaries in Indian patients. Indian Heart J. 2022 Mar-Apr;74(2):91-95. doi: 10.1016/j.ihj.2022.01.001. Epub 2022 Jan 5. PMID: 34998787; PMCID: PMC9039684.
Dr. Nandita Mohan
BDS, MDS( Pedodontics and Preventive Dentistry)
Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at firstname.lastname@example.org. Contact no. 011-43720751