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Thyroid hormone treatment connected to cardiovascular mortality

Published On 2022-05-19T10:15:48+05:30  |  Updated On 2022-05-19T14:31:28+05:30
Thyroid hormone treatment connected to cardiovascular mortality

Overview

In a population-based cohort study of 705 307 adults who received thyroid hormone treatment, 10.8% died of cardiovascular causes. Both exogenous hyperthyroidism and exogenous hypothyroidism were associated with increased risk of cardiovascular mortality.

Study published in JAMA Network Open suggest that the intensity of thyroid hormone treatment may be a modifiable risk factor for cardiovascular mortality. Two cohorts were studied: 701 929 adults aged 18 years or older who initiated thyroid hormone treatment with at least 2 thyrotropin measurements between treatment initiation and either death or the end of the study period, and, separately, 373 981 patients with at least 2 free thyroxine (FT4) measurements.

It was found that overall, 10.8% died of cardiovascular causes. After adjusting for age, sex, traditional cardiovascular risk factors patients with exogenous hyperthyroidism and patients with exogenous hypothyroidism had increased risk of cardiovascular mortality compared with individuals with euthyroidism.

Researchers concluded that this study suggests that both exogenous hyperthyroidism and exogenous hypothyroidism were associated with increased risk of cardiovascular mortality. These findings emphasize the importance of maintaining euthyroidism to decrease cardiovascular risk and death among patients receiving thyroid hormone treatment. 

Speakers

Dr. Nandita Mohan

BDS, MDS( Pedodontics and Preventive Dentistry)

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751
cardiovascular hypothyroidism cardiovascular risk thyroid hormone euthyroidism exogenous thyroid treatment JAMA Network Open 
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