Combination of oral ketotifen, famotidine with sunscreen benefits in melasma - Video

Published On 2021-11-19T16:21:10+05:30 | Updated On 21 Oct 2023 11:43 AM IST

Overview

A recent study showed that a combo of sunscreen plus oral ketotifen with famotidine improved facial melasma more than the use of sunscreen alone at 60 days. The study appears in the Journal of the European Academy of Dermatology and Venereology.

Ketotifen decreases the release of bioactive mediators, such as leukotrienes, histamine, and proteases. It has been suggested as a treatment for photoaging after being found to prevent mast cell deposition, degranulation, skin thickening, and wrinkles in UV irradiated hairless mice. Famotidine is an H2-receptor antagonist that suppresses histamine-mediated melanogenesis and dendricity in cultured human melanocytes, whereas H1 and H3 antagonists have no inhibitory effect.

For more details, check out the full story on link below:

Oral Ketotifen, Famotidine With Sunscreen Bests Sunscreen Alone For Treating Melasma : Study

Speakers

Dr. Nandita Mohan

BDS, MDS( Pedodontics and Preventive Dentistry)

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751