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Male pattern baldness linked to skin cancer risk: New research findings - Video

Published On 2023-10-06T09:00:05+05:30  |  Updated On 6 Oct 2023 9:00 AM IST
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Overview

Balding men may face a higher risk of skin cancer, according to recent research that has uncovered a surprising connection between male-pattern baldness (MPB) and skin malignancies. The study suggests that ultraviolet (UV) radiation from the sun on the scalp, rather than hormones, is the primary factor behind this increased risk.

Researchers conducted a comprehensive analysis, using a method called Mendelian randomization, to explore the potential links between MPB, hormones, and skin cancer. The study involved genetic data from thousands of individuals, including those with cutaneous melanoma and keratinocyte cancers (KCs).

Surprisingly, the results did not support a direct connection between MPB and hormones. Instead, they pointed to a strong association between MPB and the risk of KC, a group of skin cancers that includes squamous cell carcinoma and melanoma. Further analyses, breaking down the data by body site, highlighted that MPB was notably associated with head and neck squamous cell carcinoma and melanoma. This suggests that the primary driver behind the increased skin cancer risk in balding men is sun exposure on the scalp.

The study implies that men with less hair covering their scalp may be at greater risk of developing melanoma, especially in regions with high levels of ambient UV radiation. These results emphasize the importance of sun protection, particularly for individuals with male-pattern baldness.

Reference: Ong, JS., Seviiri, M., Dusingize, J.C. et al. Uncovering the complex relationship between balding, testosterone and skin cancers in men. Nat Commun 14, 5962 (2023). https://doi.org/10.1038/s41467-023-41231-8

Speakers

Isra Zaman

B.Sc Life Sciences, M.Sc Biotechnology, B.Ed

Isra Zaman is a Life Science graduate from Daulat Ram College, Delhi University, and a postgraduate in Biotechnology from Amity University. She has a flair for writing, and her roles at Medicaldialogues include that of a Sr. content writer and a medical correspondent. Her news pieces cover recent discoveries and updates from the health and medicine sector. She can be reached at editorial@medicaldialogues.in.

Dr. Kamal Kant Kohli

Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News. Besides writing articles, as an editor, he proofreads and verifies all the medical content published on Medical Dialogues including those coming from journals, studies,medical conferences,guidelines etc. Email: drkohli@medicaldialogues.in. Contact no. 011-43720751
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